4-Fluoro-1-naphthoic acid
4-Fluoro-1-naphthoic acid (CAS: 573-03-5), with the molecular formula FC₁₀H₆CO₂H and a molecular weight of 190.17 g/mol, is a fluorinated organic building block. This compound is recognised for its utility in chemical synthesis and research applications. Notably, it functions as an inhibitor of Yersinia PTP YopH, with an observed IC 50 value.
Yersinia PTP YopH Inhibition
4-Fluoro-1-naphthoic acid has been identified as an inhibitor of the Yersinia protein tyrosine phosphatase YopH. Its inhibitory activity is quantified by an IC 50 value, indicating its potential in biochemical research studies concerning this enzyme.
Organic Synthesis Intermediate
As a fluorinated naphthoic acid derivative, this compound serves as a valuable building block in organic synthesis. Its structure allows for further functionalisation in the creation of more complex molecules for various research and development purposes.
Fluorinated Building Block
This chemical belongs to the class of aryl fluorinated building blocks. The presence of fluorine and the naphthoic acid moiety makes it a useful starting material for synthesising novel organic compounds with specific electronic or steric properties.
| Molecular weight | 190.17 |
|---|---|
| Linear formula | FC10H6CO2H |
| Assay | 96% |
| Application | 4-Fluoro-1-naphthoic acid is an inhibitor of Yersinia PTP YopH. It contains an extended aromatic system and its IC50 value was measured1. |
| Melting point | 224-227 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Fluoro-1-naphthoic acid used for?
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4-Fluoro-1-naphthoic acid is used as an inhibitor of Yersinia PTP YopH and as a building block in organic synthesis, particularly for creating fluorinated organic compounds.
What are the CAS number and molecular formula for 4-Fluoro-1-naphthoic acid?
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The CAS number is 573-03-5 and the molecular formula is FC₁₀H₆CO₂H.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-Fluoro-1-naphthoic acid with an assay of 96%. This product is not supplied in USP, BP, EP, pharmacopoeia, nutraceutical, or food grades.
What are the safety considerations for handling 4-Fluoro-1-naphthoic acid?
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Handling 4-Fluoro-1-naphthoic acid requires precautions due to potential skin, eye, and respiratory irritation (H315, H319, H335). Recommended personal protective equipment includes a dust mask (type N95), eyeshields, and gloves. Ensure adequate ventilation.
Can Tech Serve Solutions export 4-Fluoro-1-naphthoic acid?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals and laboratory reagents, including 4-Fluoro-1-naphthoic acid.
How can I request a sample or quote for 4-Fluoro-1-naphthoic acid?
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To request a sample or obtain a quotation for 4-Fluoro-1-naphthoic acid, please contact our sales department through the website or by phone.
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