4-Chlorophenylacetyl chloride
4-Chlorophenylacetyl chloride (CAS: 25026-34-0) is a chemical compound with the formula C8H6Cl2O and a molecular weight of 189.04 g/mol. This acid halide serves as a valuable organic building block in chemical synthesis. Its reactive nature makes it suitable for introducing the 4-chlorophenylacetyl group into various molecules. It is primarily used in research and development settings for the creation of more complex chemical structures.

Organic Synthesis Intermediate
4-Chlorophenylacetyl chloride is utilized as a reactive intermediate in the synthesis of complex organic molecules. Its acyl chloride functionality allows for facile acylation reactions.
Pharmaceutical Research
This compound can be employed in the early stages of drug discovery and development for the synthesis of novel pharmaceutical candidates. It acts as a key building block for introducing specific structural motifs.
Agrochemical Development
The compound may find application in the development of new agrochemicals. Its structure lends itself to modification for creating compounds with potential pesticidal or herbicidal activity.
| Molecular weight | 189.04 |
|---|---|
| Empirical formula | C8H6Cl2O |
| Assay | 97% |
| Boiling point | 85 °C/1 mmHg(lit.) |
| Density | 1.292 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.5510(lit.) |


Hazard statements
- H302Harmful if swallowed
- H314Causes severe skin burns and eye damage
- H317May cause an allergic skin reaction
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | >110 °C / >230 °F |
| Transport (UN / ADR) | UN 3265 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 22-34-43 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Chlorophenylacetyl chloride used for?
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4-Chlorophenylacetyl chloride is primarily used as a reactive intermediate in organic synthesis, particularly in pharmaceutical and agrochemical research, for introducing the 4-chlorophenylacetyl moiety into other molecules.
What are the CAS number and formula for 4-Chlorophenylacetyl chloride?
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The CAS number is 25026-34-0 and the empirical formula is C8H6Cl2O.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-Chlorophenylacetyl chloride with an assay of 97%. We do not represent this product as USP, BP, or EP grade.
How should 4-Chlorophenylacetyl chloride be handled?
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4-Chlorophenylacetyl chloride is a dangerous substance (Danger) that causes severe skin burns and eye damage, and may cause an allergic skin reaction. It is also harmful if swallowed. Appropriate personal protective equipment, including gloves, goggles, and a respirator, must be used. Handle in a well-ventilated area.
How is 4-Chlorophenylacetyl chloride packed and shipped?
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4-Chlorophenylacetyl chloride is shipped as UN 3265, Class 8, Packing Group II, under regulations for corrosive liquids, acidic, organic, n.o.s. Our export team ensures compliance with all international shipping regulations.
How can I request a sample or quote for 4-Chlorophenylacetyl chloride?
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To request a sample or a quote for 4-Chlorophenylacetyl chloride, please contact our sales department through the website or by phone, providing your specific requirements.
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