4-Chloro-3-ethylphenol
4-Chloro-3-ethylphenol (CAS: 14143-32-9; Formula: ClC6H3(C2H5)OH) is a chlorinated phenol with a molecular weight of 156.61 g/mol. This compound functions as a ryanodine receptor antagonist, making it a valuable research tool. It is primarily utilised in scientific investigations and as a diagnostic reagent for conditions such as malignant hyperthermia. Tech Serve Solutions offers this chemical with a purity of 97%.

Research Tool
As a ryanodine receptor antagonist, 4-Chloro-3-ethylphenol is employed in biochemical and pharmacological research to study cellular signalling pathways and receptor function.
Diagnostic Reagent
This compound serves as a diagnostic reagent in the identification and study of malignant hyperthermia, a critical genetic disorder affecting skeletal muscle. Its specific interaction with ryanodine receptors is key to this application.
Chemical Synthesis
4-Chloro-3-ethylphenol is an organic building block suitable for various chemical synthesis applications, particularly in the development of more complex molecules within organic chemistry.
| Molecular weight | 156.61 |
|---|---|
| Linear formula | ClC6H3(C2H5)OH |
| Assay | 97% |
| Application | 4-Chloro-3-ethylphenol is a ryanodine receptor antagonist and is commonly used as research tool and diagnostic reagent for malignant hyperthermia1. |
| Melting point | 45-50 °C(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Flash point | 113 °C / 235.4 °F |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Chloro-3-ethylphenol used for?
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4-Chloro-3-ethylphenol is used as a research tool and a diagnostic reagent for malignant hyperthermia due to its function as a ryanodine receptor antagonist. It is also applicable in chemical synthesis.
What are the CAS number and formula for 4-Chloro-3-ethylphenol?
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The CAS number for 4-Chloro-3-ethylphenol is 14143-32-9, and its linear formula is ClC6H3(C2H5)OH.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-Chloro-3-ethylphenol at an assay of 97%. This is a technical grade chemical and is not represented as USP, BP, or EP.
How should 4-Chloro-3-ethylphenol be handled safely?
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Handling requires appropriate personal protective equipment including a dust mask type N95 (US), eyeshields, and gloves. It is classified as a warning substance that causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335).
Does TSS export 4-Chloro-3-ethylphenol?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including 4-Chloro-3-ethylphenol.
How can I request a quote or sample?
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Please contact Tech Serve Solutions directly through our website or by phone to request a quote or a sample of 4-Chloro-3-ethylphenol.
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