4-Chloro-3-Fluorobenzaldehyde
4-Chloro-3-Fluorobenzaldehyde (CAS 5527-95-7), with the molecular formula ClC6H3(F)CHO and a molar mass of 158.56 g/mol, is a fluorinated aromatic aldehyde. This compound serves as a valuable building block in organic synthesis. It is primarily utilised in the development of new chemical entities, particularly within the pharmaceutical and agrochemical industries, owing to the presence of both halogen substituents and a reactive aldehyde group.

Pharmaceutical Intermediate
Used in the synthesis of active pharmaceutical ingredients (APIs) and complex drug molecules. The specific arrangement of fluorine and chlorine atoms on the benzaldehyde core allows for targeted modifications in drug discovery programmes.
Agrochemical Synthesis
Acts as a key intermediate in the production of novel pesticides, herbicides, and fungicides. The fluorinated aromatic structure can impart desirable properties such as enhanced efficacy and metabolic stability to agrochemical products.
Organic Building Block
Serves as a versatile starting material for various organic transformations. Its aldehyde functionality readily participates in reactions like condensations, reductions, and oxidations, enabling the construction of diverse molecular architectures.
Materials Science Research
Potentially employed in the development of specialised polymers or functional materials where specific electronic or structural properties are required. Its unique substitution pattern may influence material characteristics.
| Molecular weight | 158.56 |
|---|---|
| Linear formula | ClC6H3(F)CHO |
| Assay | 97% |
| Melting point | 46-49 °C(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Flash point | 96 °C / 204.8 °F |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Chloro-3-Fluorobenzaldehyde used for?
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4-Chloro-3-Fluorobenzaldehyde is primarily used as a building block in organic synthesis, particularly for the development of pharmaceuticals and agrochemicals. It is also employed in materials science research.
What are the CAS number and chemical formula for 4-Chloro-3-Fluorobenzaldehyde?
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The CAS number is 5527-95-7, and the chemical formula is ClC6H3(F)CHO.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-Chloro-3-Fluorobenzaldehyde with a minimum assay of 97%. This is a technical/research grade chemical, and TSS does not represent it as USP, BP, EP, or any other pharmacopoeia standard.
How should 4-Chloro-3-Fluorobenzaldehyde be handled safely?
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Handle with appropriate personal protective equipment, including eyeshields, gloves, and a dust mask (type N95 or equivalent). Avoid breathing dust. Ensure adequate ventilation. This compound is classified as an irritant to the skin, eyes, and respiratory system (H315-H319-H335).
Is 4-Chloro-3-Fluorobenzaldehyde shipped internationally?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including 4-Chloro-3-Fluorobenzaldehyde. We handle all export and shipping requirements.
How can I request a quote or sample for 4-Chloro-3-Fluorobenzaldehyde?
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To request a quote or a sample, please contact our sales team through the website or by phone, providing your details and the product name or CAS number (5527-95-7).
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