4-Chloro-3-fluoropyridine
4-Chloro-3-fluoropyridine (CAS: 2546-56-7) is a halogenated heterocyclic compound with the molecular formula C5H3ClFN and a molecular weight of 131.54 g/mol. This fluorinated pyridine derivative serves as a valuable building block in organic synthesis, particularly in the development of novel agrochemicals and pharmaceuticals. Its specific substitution pattern allows for diverse chemical transformations, making it a key intermediate in complex molecule construction.
Organic Synthesis Intermediate
This compound functions as a versatile building block in various organic synthesis pathways. It is employed in the creation of more complex heterocyclic structures relevant to medicinal chemistry and material science.
Agrochemical Development
4-Chloro-3-fluoropyridine is utilised in the synthesis of active ingredients for agrochemicals. Its fluorinated pyridine core can impart desirable properties such as enhanced efficacy and metabolic stability to the final pesticide or herbicide.
Pharmaceutical Research
It serves as a key intermediate in the research and development of new pharmaceutical agents. The incorporation of the fluoropyridine moiety can influence the pharmacokinetic and pharmacodynamic profiles of drug candidates.
| Molecular weight | 131.54 |
|---|---|
| Empirical formula | C5H3ClFN |
| Assay | ≥95.0% |
| Density | 1.333 g/mL at 25 °C(lit.) |
Hazard statements
- H226Flammable liquid and vapour
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 28 °C / 82.4 °F |
| Transport (UN / ADR) | UN 1993C 3 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 10-36/37/38 |
| Safety statements (S) | 16-26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Chloro-3-fluoropyridine used for?
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4-Chloro-3-fluoropyridine is primarily used as a building block in organic synthesis, particularly in the development of agrochemicals and pharmaceuticals. It is valuable for creating more complex heterocyclic structures.
What is the CAS number and formula for 4-Chloro-3-fluoropyridine?
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The CAS number for 4-Chloro-3-fluoropyridine is 2546-56-7 and its empirical formula is C5H3ClFN.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-Chloro-3-fluoropyridine with an assay of ≥95.0%. This product is intended for research and technical use; TSS does not represent it as USP, BP, EP, or pharmaceutical grade.
What are the safety and handling considerations for 4-Chloro-3-fluoropyridine?
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This compound is a flammable liquid (flash point 28°C) and is classified as a warning substance. It causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Appropriate personal protective equipment, including safety goggles, gloves, and suitable respiratory protection, must be used. Handle in a well-ventilated area away from ignition sources.
How is 4-Chloro-3-fluoropyridine packed, shipped, and exported?
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4-Chloro-3-fluoropyridine is packed and shipped according to international regulations for hazardous materials, including UN 1993 classification. As a global supplier, Tech Serve Solutions handles all necessary export documentation and logistics.
How can I request a sample or quote for 4-Chloro-3-fluoropyridine?
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To request a sample or a quote for 4-Chloro-3-fluoropyridine, please visit the Tech Serve Solutions website or contact our sales department directly.
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