4-Chloro-3-fluorophenol
4-Chloro-3-fluorophenol (CAS: 348-60-7; Formula: ClC6H3(F)OH) is a halogenated phenol with a molecular weight of 146.55 g/mol. This compound serves as a valuable building block in organic synthesis, particularly within the fields of pharmaceuticals and agrochemicals. Its structure, featuring both chlorine and fluorine substituents on a phenol ring, allows for diverse chemical transformations. Available at 98% purity, it is suitable for research and development purposes.
Synthesis of Catechol Derivatives
4-Chloro-3-fluorophenol has been utilised as a precursor in the synthesis of specific catechol derivatives, such as 4-chloro-3-fluoro catechol. This highlights its utility in creating more complex fluorinated aromatic compounds.
Fluorinated Organic Building Block
As an organic fluorinated building block, this compound is employed in multi-step synthesis pathways. The presence of fluorine and chlorine atoms offers distinct reactivity for the construction of novel molecules.
Research and Development
The compound is utilised in laboratory settings for research and development activities. Its specific substitution pattern makes it a useful intermediate for exploring new chemical entities and reaction methodologies.
| Molecular weight | 146.55 |
|---|---|
| Linear formula | ClC6H3(F)OH |
| Assay | 98% |
| Boiling point | 84 °C/44 mmHg(lit.) |
| Solubility | chloroform: soluble50 mg/mL, clear, colorless |
| Application | 4-Chloro-3-fluorophenol was used in the synthesis of 4-chloro-3-fluoro catechol1. |
| Melting point | 54-56 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Flash point | 113 °C / 235.4 °F |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Chloro-3-fluorophenol used for?
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4-Chloro-3-fluorophenol is primarily used as a building block in organic synthesis, including the preparation of 4-chloro-3-fluoro catechol and other complex fluorinated organic compounds for research and development.
What are the CAS number and formula for 4-Chloro-3-fluorophenol?
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The CAS number for 4-Chloro-3-fluorophenol is 348-60-7, and its chemical formula is ClC6H3(F)OH.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-Chloro-3-fluorophenol with an assay of 98%. We do not represent this product as USP, BP, EP, or any other pharmacopoeial grade.
How should 4-Chloro-3-fluorophenol be handled safely?
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4-Chloro-3-fluorophenol is a Warning substance (GHS07) with hazards H315 (causes skin irritation), H319 (causes serious eye irritation), and H335 (may cause respiratory irritation). Recommended personal protective equipment includes a dust mask type N95 (US), eyeshields, and gloves. Ensure adequate ventilation and avoid breathing dust.
How is 4-Chloro-3-fluorophenol packed, shipped, and exported?
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Tech Serve Solutions expertly packs, ships, and exports 4-Chloro-3-fluorophenol globally, adhering to all relevant regulations for hazardous materials.
How can I request a sample or quote for 4-Chloro-3-fluorophenol?
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To request a sample or a quote for 4-Chloro-3-fluorophenol, please contact our sales team via the website or direct email, providing your specific requirements.
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