4-Bromo-2-(trifluoromethoxy)aniline
4-Bromo-2-(trifluoromethoxy)aniline (CAS: 175278-09-8), with the molecular formula C7H5BrF3NO, is a versatile organic building block. This compound, characterised by its bromo and trifluoromethoxy substituents on an aniline core, serves as a key intermediate in complex organic synthesis. It is particularly valuable in the development of novel chemical entities, contributing to advancements in pharmaceutical and material science research. TSS supplies this chemical for laboratory and industrial applications.

Pharmaceutical Intermediate
Serves as a crucial building block in the synthesis of active pharmaceutical ingredients (APIs). Its unique structure allows for the introduction of specific functionalities into drug candidates, aiding in the development of novel therapeutics.
Agrochemical Synthesis
Used in the research and development of new agrochemicals. The trifluoromethoxy and bromo groups can impart desirable properties for crop protection agents, contributing to improved agricultural outcomes.
Material Science Research
Employed in the creation of advanced materials. The incorporation of fluorinated and brominated aromatic amines can lead to polymers and specialty chemicals with tailored electronic or physical properties.
Organic Synthesis Reagent
A valuable reagent for general organic synthesis, enabling chemists to construct complex molecular architectures. It is useful in cross-coupling reactions and other transformations requiring functionalized anilines.
| Molecular weight | 256.02 |
|---|---|
| Empirical formula | C7H5BrF3NO |
| Assay | 97% |
| Boiling point | 98-100 °C/15 mmHg(lit.) |
| Density | 1.691 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.5130(lit.) |

Hazard statements
- H301Toxic if swallowed
- H317May cause an allergic skin reaction
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P301IF SWALLOWED
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | >110 °C / >230 °F |
| Transport (UN / ADR) | UN 2810 6.1 / PGIII |
| Water hazard class (WGK, DE) | 2 |
| Hazard codes (EU) | T |
| Risk statements (R) | 25-43-52/53 |
| Safety statements (S) | 36/37-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Bromo-2-(trifluoromethoxy)aniline used for?
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4-Bromo-2-(trifluoromethoxy)aniline is primarily used as a building block in organic synthesis, particularly in the development of pharmaceuticals, agrochemicals, and advanced materials. Its specific structure makes it valuable for introducing brominated and trifluoromethoxylated phenyl rings into target molecules.
What are the CAS number and formula for this chemical?
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The CAS number for 4-Bromo-2-(trifluoromethoxy)aniline is 175278-09-8. Its empirical formula according to Hill notation is C7H5BrF3NO.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-Bromo-2-(trifluoromethoxy)aniline with an assay of 97%. TSS does not represent this product as USP, BP, EP, or for food or pharmaceutical use unless explicitly stated.
What are the primary hazards associated with 4-Bromo-2-(trifluoromethoxy)aniline?
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This compound is classified with the GHS symbol GHS06 and the signal word Danger. It carries hazard statements H301 (Toxic if swallowed) and H317 (May cause an allergic skin reaction). Appropriate personal protective equipment, including eyeshields, face shields, and suitable gloves and respirators, is required for safe handling. Refer to the Safety Data Sheet for comprehensive information.
Is 4-Bromo-2-(trifluoromethoxy)aniline a controlled substance?
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The provided data does not indicate that 4-Bromo-2-(trifluoromethoxy)aniline is a scheduled or controlled substance.
How is this chemical packed, shipped, and exported?
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As a specialist global supplier, TSS ensures that 4-Bromo-2-(trifluoromethoxy)aniline is packed, handled, and shipped in compliance with all relevant international regulations for hazardous materials, including UN 2810 classification.
How can I request a quote or sample?
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To request a quote or sample of 4-Bromo-2-(trifluoromethoxy)aniline, please contact the Tech Serve Solutions sales team via our website or direct inquiry channels.
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