4-Bromo-2,8-bis(trifluoromethyl)quinoline
4-Bromo-2,8-bis(trifluoromethyl)quinoline (CAS: 35853-45-3) is a halogenated heterocyclic building block with the molecular formula C11H4BrF6N and a molecular weight of 344.05 g/mol. This compound, typically supplied at 95% assay, serves as a valuable intermediate in organic synthesis. Its trifluoromethyl and bromo substitutions make it useful for creating complex molecules in research and development, particularly within the fields of medicinal chemistry and materials science.
- Synonyms
- C11H4BrF6N

Organic Synthesis Intermediate
Utilised as a versatile building block in the synthesis of more complex organic molecules. The presence of a bromine atom and trifluoromethyl groups allows for diverse chemical transformations.
Medicinal Chemistry Research
Serves as a scaffold or intermediate in the development of novel pharmaceutical agents. The quinoline core and fluorine substituents can influence biological activity and pharmacokinetic properties.
Materials Science
Investigated for potential use in the development of new materials, such as organic electronic components, owing to its specific electronic and structural characteristics conferred by the trifluoromethyl groups.
| Molecular weight | 344.05 |
|---|---|
| Empirical formula | C11H4BrF6N |
| Assay | 95% |
| Melting point | 62-64 °C(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Bromo-2,8-bis(trifluoromethyl)quinoline used for?
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4-Bromo-2,8-bis(trifluoromethyl)quinoline is primarily used as a building block in organic synthesis, particularly in medicinal chemistry research and potentially in materials science.
What are the CAS number and formula for this compound?
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The CAS number is 35853-45-3, and the empirical formula is C11H4BrF6N.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-Bromo-2,8-bis(trifluoromethyl)quinoline at a minimum assay of 95%. We do not represent this product as meeting USP, BP, EP, or any other pharmacopoeia standards.
How should 4-Bromo-2,8-bis(trifluoromethyl)quinoline be handled?
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This compound is classified with Warning signal word, and hazard statements H315, H319, H335, indicating it causes skin irritation, serious eye irritation, and may cause respiratory irritation. Appropriate personal protective equipment including a dust mask (type N95 US), eyeshields, and gloves should be used. Ensure good ventilation.
Is 4-Bromo-2,8-bis(trifluoromethyl)quinoline a controlled substance?
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Based on the provided data, there is no indication that 4-Bromo-2,8-bis(trifluoromethyl)quinoline is a controlled substance.
How is this chemical exported and shipped?
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As a global supplier and exporter of fine chemicals since 1998, Tech Serve Solutions adheres to all necessary regulations for the safe and compliant export and shipment of chemical products worldwide.
How can I request a sample or quote for this product?
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To request a sample or obtain a quotation for 4-Bromo-2,8-bis(trifluoromethyl)quinoline, please contact our sales team via the website or directly through our published contact details.
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