4-Bromo-2-(tributylstannyl)thiazole
4-Bromo-2-(tributylstannyl)thiazole (CAS: 173978-98-8) is an organotin compound with the empirical formula C15H28BrNSSn and a molecular weight of 453.07 g/mol. This reagent is primarily utilised in chemical synthesis, particularly for introducing the 2-thiazolyl moiety into organic molecules via cross-coupling reactions. Its properties make it a valuable intermediate in the development of complex organic structures.
Organic Synthesis Intermediate
This compound serves as a key building block in organic synthesis, enabling the formation of new carbon-carbon bonds. It is particularly useful in cross-coupling reactions such as Stille coupling for the synthesis of complex organic molecules.
Heterocyclic Chemistry
It is employed in the synthesis of functionalised thiazole derivatives, which are prevalent in pharmaceuticals and agrochemicals. The bromo and stannyl groups offer distinct points for further chemical transformations.
Research and Development
Utilised in academic and industrial research laboratories for exploring novel synthetic methodologies and developing new chemical entities with potential biological activities.
| Molecular weight | 453.07 |
|---|---|
| Empirical formula | C15H28BrNSSn |
| Density | 1.314 g/mL at 25 °C |
| Refractive index | n20/D 1.527 |
Hazard statements
- H301Toxic if swallowed
- H312Harmful in contact with skin
- H315Causes skin irritation
- H319Causes serious eye irritation
- H372Causes damage to organs through prolonged exposure
- H410Very toxic to aquatic life with long-lasting effects
Precautionary statements
- P273Avoid release to the environment
- P280Wear protective gloves, clothing and eye/face protection
- P301IF SWALLOWED
- P305IF IN EYES
- P314Get medical attention if you feel unwell
- P501Dispose of contents and container per local regulations
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | >110 °C / >230 °F |
| Transport (UN / ADR) | UN 2788 6.1 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T,N |
| Risk statements (R) | 21-25-36/38-48/23/25-50/53 |
| Safety statements (S) | 35-36/37/39-45-60-61 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Bromo-2-(tributylstannyl)thiazole used for?
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4-Bromo-2-(tributylstannyl)thiazole is primarily used as an intermediate in organic synthesis, particularly for introducing the 2-thiazolyl group into molecules via reactions like the Stille coupling. It is also used in research and development for creating novel heterocyclic compounds.
What is the CAS number and empirical formula for 4-Bromo-2-(tributylstannyl)thiazole?
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The CAS number is 173978-98-8 and the empirical formula is C15H28BrNSSn.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-Bromo-2-(tributylstannyl)thiazole. The specific assay and purity are detailed in the product's Certificate of Analysis. We do not represent this product as USP, BP, or EP grade.
How should 4-Bromo-2-(tributylstannyl)thiazole be handled?
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This compound is classified as Danger, with hazards including acute toxicity (oral and dermal), skin and eye irritation, and potential organ damage with prolonged exposure, along with significant environmental toxicity. Handle with appropriate personal protective equipment, including eyeshields, gloves, and a suitable respirator. Ensure adequate ventilation and avoid release into the environment.
Is 4-Bromo-2-(tributylstannyl)thiazole packed and shipped internationally?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, and we can arrange for the packing and export of 4-Bromo-2-(tributylstannyl)thiazole according to international regulations.
How can I request a quote or sample?
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To request a quote or a sample of 4-Bromo-2-(tributylstannyl)thiazole, please contact our sales team through the website or by phone, providing your contact details and the quantity required.
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