4-Bromo-2-(trifluoromethyl)aniline
4-Bromo-2-(trifluoromethyl)aniline (CAS: 445-02-3), with the chemical formula BrC6H3(CF3)NH2 and a molecular weight of 240.02 g/mol, is a valuable organic compound. It serves as a key building block in chemical synthesis, particularly for introducing trifluoromethyl and bromine functionalities into organic molecules. Its applications are primarily within research and development settings for creating more complex chemical structures.
Synthesis of Halogenated Aromatics
4-Bromo-2-(trifluoromethyl)aniline is utilised in the preparation of various halogenated aromatic compounds, demonstrating its utility as a versatile synthetic intermediate.
Intermediate for Organic Synthesis
This compound acts as a fundamental building block in multi-step organic syntheses, enabling the construction of complex molecules for diverse research applications.
Preparation of Substituted Benzenes
It has been employed in specific synthetic routes, for instance, in the preparation of compounds such as 2,5-dibromo-(trifluoromethyl)benzene and 5-bromo-2-iodo-(trifluoromethyl)benzene.
| Molecular weight | 240.02 |
|---|---|
| Linear formula | BrC6H3(CF3)NH2 |
| Assay | 97% |
| Boiling point | 84-86 °C/5 mmHg(lit.) |
| Density | 1.71 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.532(lit.) |
| Application | 4-Bromo-2-(trifluoromethyl)aniline has been used in the preparation of 2,5-dibromo-(trifluoromethyl)benzene and 5-bromo-2-iodo-(trifluoromethyl)benzene1. |
Hazard statements
- H302Harmful if swallowed
- H312Harmful in contact with skin
- H315Causes skin irritation
- H319Causes serious eye irritation
- H332Harmful if inhaled
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 107 °C / 224.6 °F |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 20/21/22-36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Bromo-2-(trifluoromethyl)aniline used for?
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4-Bromo-2-(trifluoromethyl)aniline is primarily used as a building block in organic synthesis, particularly for the preparation of complex halogenated aromatic compounds and substituted benzenes.
What is the CAS number and chemical formula for 4-Bromo-2-(trifluoromethyl)aniline?
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The CAS number is 445-02-3, and the chemical formula is BrC6H3(CF3)NH2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-Bromo-2-(trifluoromethyl)aniline with a minimum assay of 97%. This product is intended for laboratory and research use and is not supplied as USP, BP, or EP grade.
What are the primary safety concerns when handling 4-Bromo-2-(trifluoromethyl)aniline?
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This compound is classified with a 'Warning' signal word and carries hazard statements H302, H312, H315, H319, H332, and H335, indicating it is harmful if swallowed, in contact with skin, or if inhaled, and causes skin and serious eye irritation, as well as potential respiratory irritation. Appropriate personal protective equipment, including eyeshields, gloves, and a suitable respirator, is essential.
Is 4-Bromo-2-(trifluoromethyl)aniline a controlled substance?
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The provided data does not indicate that 4-Bromo-2-(trifluoromethyl)aniline is a controlled substance. However, users should always verify local regulations.
How can I request a quote or sample for 4-Bromo-2-(trifluoromethyl)aniline?
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To request a quote or sample, please contact the Tech Serve Solutions sales team via our website or direct inquiry channels. We export globally.
What are the physical properties of 4-Bromo-2-(trifluoromethyl)aniline?
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Key physical properties include a boiling point of 84-86 °C/5 mmHg, a density of 1.71 g/mL at 25 °C, and a refractive index of n20/D 1.532.
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