4-Aminocinnamic acid hydrochloride
4-Aminocinnamic acid hydrochloride (CAS: 54057-95-3) is a chemical compound with the molecular formula H₂NC₆H₄CH=CHCO₂H · HCl and a molecular weight of 199.63 g/mol. It is recognised for its utility in chemical synthesis and peptide chemistry. This compound serves as a valuable building block in organic chemistry, particularly in the creation of novel molecules and modified amino acid structures.

Chemical Synthesis Intermediate
4-Aminocinnamic acid hydrochloride is employed as a key intermediate in various organic synthesis pathways. Its structure allows for diverse chemical modifications, facilitating the construction of complex organic molecules.
Peptide Chemistry Applications
This compound is utilised in peptide chemistry for the incorporation of unnatural amino acid derivatives. It can be used to modify peptide sequences, introducing new properties or functionalities for research purposes.
Research and Development
As a specialised chemical reagent, 4-Aminocinnamic acid hydrochloride finds application in research and development laboratories. Its properties make it suitable for exploring new chemical reactions and developing novel materials.
| Molecular weight | 199.63 |
|---|---|
| Linear formula | H2NC6H4CH=CHCO2H · HCl |
| Assay | 97% |
| Melting point | 265-270 °C (dec.)(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Aminocinnamic acid hydrochloride used for?
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4-Aminocinnamic acid hydrochloride is used in chemical synthesis, peptide chemistry, and for research and development purposes, particularly as an unnatural amino acid derivative.
What is the CAS number and formula for 4-Aminocinnamic acid hydrochloride?
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The CAS number is 54057-95-3 and the linear formula is H₂NC₆H₄CH=CHCO₂H · HCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-Aminocinnamic acid hydrochloride with an assay of 97%. TSS does not represent this product as USP, BP, EP, or any pharmacopoeia grade.
How should 4-Aminocinnamic acid hydrochloride be handled safely?
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Handle with appropriate personal protective equipment, including a dust mask type N95 (US), eyeshields, and gloves. Avoid breathing dust. Ensure adequate ventilation. This compound may cause skin irritation, eye irritation, and respiratory irritation (H315, H319, H335).
Is 4-Aminocinnamic acid hydrochloride packed and shipped internationally?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including 4-Aminocinnamic acid hydrochloride, and can facilitate international shipping.
How can I request a sample or quote for 4-Aminocinnamic acid hydrochloride?
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To request a sample or quote, please contact the Tech Serve Solutions sales team through our official website or direct contact channels.
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