4,4′-Trimethylenedipiperidine
4,4′-Trimethylenedipiperidine (CAS: 16898-52-5) is a valuable heterocyclic building block with the molecular formula C13H26N2 and a molecular weight of 210.36 g/mol. This chemical is primarily utilised in advanced synthesis applications. Its structure lends itself to the creation of complex molecular architectures, including hyperbranched copolymers and metal-organic frameworks, making it a key intermediate for researchers in materials science and organic chemistry.
- IUPAC
- 1,3-Bis(4-piperidyl)propane,1,3-Di-4-piperidylpropane
- Synonyms
- 1,3-Bis(4-piperidyl)propane1,3-Di-4-piperidylpropane

Synthesis of Hyperbranched Copolymers
4,4′-Trimethylenedipiperidine has been employed in the synthesis of hyperbranched copolymers. It reacts with monomers such as divinylsulfone and N-ethylenediamine to form these complex polymeric structures.
Development of Metal-Organic Frameworks
This compound serves as a building block for constructing two- and three-dimensional cadmium-organic frameworks. These materials are of interest for their potential applications in various scientific fields.
Heterocyclic Synthesis
As a piperidine derivative, 4,4′-Trimethylenedipiperidine is a versatile intermediate in the synthesis of diverse heterocyclic compounds.
| Molecular weight | 210.36 |
|---|---|
| Empirical formula | C13H26N2 |
| Assay | 97% |
| Application | 4,4′-Trimethylenedipiperidine was used in the synthesis of hyperbranched copolymers from commercially available monomers: divinylsulfone, 4,4′-trimethylenedipiperidine and N-ethylenediamine1. It was used in the synthesis of two- and three-dimensional cadmium-organic frameworks2. |
| Melting point | 65-68.5 °C(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4,4′-Trimethylenedipiperidine used for?
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4,4′-Trimethylenedipiperidine is used as a building block in chemical synthesis, notably for creating hyperbranched copolymers and metal-organic frameworks.
What are the CAS number and formula for 4,4′-Trimethylenedipiperidine?
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The CAS number for 4,4′-Trimethylenedipiperidine is 16898-52-5 and its empirical formula is C13H26N2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4,4′-Trimethylenedipiperidine with a minimum assay of 97%. This product is typically supplied for research and chemical synthesis purposes and is not represented as USP, BP, or EP grade.
How should 4,4′-Trimethylenedipiperidine be handled safely?
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4,4′-Trimethylenedipiperidine is a warning substance that may cause skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). Appropriate personal protective equipment, including a dust mask (N95), eyeshields, and gloves, should be used. Ensure adequate ventilation.
Is 4,4′-Trimethylenedipiperidine a controlled substance?
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Based on the provided data, 4,4′-Trimethylenedipiperidine is not listed as a controlled substance. However, users should always verify local regulations.
How is 4,4′-Trimethylenedipiperidine packed and shipped?
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4,4′-Trimethylenedipiperidine is carefully packed to ensure safe transit and is exported globally by Tech Serve Solutions. Specific packaging details are available upon request.
How can I request a sample or quote for 4,4′-Trimethylenedipiperidine?
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To request a sample or a quote for 4,4′-Trimethylenedipiperidine, please contact the Tech Serve Solutions sales team through our website or by phone.
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