4,4′-Trimethylenebis(1-methylpiperidine)
4,4′-Trimethylenebis(1-methylpiperidine) (CAS: 64168-11-2) is a heterocyclic organic compound with the molecular formula C15H30N2. This chemical, with a molecular weight of 238.41 g/mol, serves as a valuable building block in chemical synthesis. Its applications span the creation of novel cyanine dyes for biological detection, the development of structure-directing agents, and the synthesis of piperidine-based dicationic ionic liquids, highlighting its versatility in advanced materials and research.
- IUPAC
- 4,4′-(1,3-Propanediyl)bis[1-methyl-piperidine]
- Synonyms
- 4,4′-(1,3-Propanediyl)bis[1-methyl-piperidine]

Synthesis of Cyanine Dyes
This compound is utilised in the synthesis of di-, tri-, and tetracationic monomeric and homodimeric monomethine cyanine dyes. These dyes are primarily employed for nucleic acid detection in various biological and diagnostic applications.
Development of Structure Directing Agents
4,4′-Trimethylenebis(1-methylpiperidine) has been incorporated into the design and synthesis of specialised structure directing agents. These agents are crucial in materials science for controlling crystallisation and morphology.
Ionic Liquids Research
The compound serves as a precursor in the synthesis of piperidine-based dicationic ionic liquids. These ionic liquids are explored for their unique properties and potential applications in catalysis and electrochemical systems.
| Molecular weight | 238.41 |
|---|---|
| Empirical formula | C15H30N2 |
| Assay | ≥98% |
| Boiling point | 215 °C/50 mmHg(lit.) |
| Density | 0.896 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.482(lit.) |
| Application | 4,4′-Trimethylenebis(1-methylpiperidine) has been used in the synthesis of:• di-, tri- and tetracationic monomeric and homodimeric monomethine cyanine dyes for nucleic acid detection1• structure directing agents containing 4,4′-trimethylenebis(1-methylpiperidine)2• piperidine-based dicationic ionic liquids3 |
| Melting point | 13 °C(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 113 °C / 235.4 °F |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4,4′-Trimethylenebis(1-methylpiperidine) used for?
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4,4′-Trimethylenebis(1-methylpiperidine) is used as a building block in chemical synthesis, particularly for creating cyanine dyes used in nucleic acid detection, structure directing agents, and piperidine-based dicationic ionic liquids.
What is the CAS number and formula for 4,4′-Trimethylenebis(1-methylpiperidine)?
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The CAS number is 64168-11-2 and the empirical formula is C15H30N2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4,4′-Trimethylenebis(1-methylpiperidine) with an assay of ≥98%. We do not represent this product as USP, BP, or EP grade.
What are the safety considerations when handling 4,4′-Trimethylenebis(1-methylpiperidine)?
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This compound is classified with GHS07 symbol and a Warning signal word. It carries hazard statements H315 (Causes skin irritation), H319 (Causes serious eye irritation), and H335 (May cause respiratory irritation). Appropriate personal protective equipment including eyeshields, gloves, and suitable respiratory protection should be used.
How is 4,4′-Trimethylenebis(1-methylpiperidine) packed, shipped, or exported?
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Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, adhering to all relevant regulations for safe packing, shipping, and export.
How can I request a sample or quote for 4,4′-Trimethylenebis(1-methylpiperidine)?
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To request a sample or quote, please contact our sales team through the website or by phone, providing the product name and CAS number (64168-11-2).
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