2-Acetyl-5-chlorothiophene
2-Acetyl-5-chlorothiophene (CAS: 6310-09-4) is a halogenated heterocyclic building block with the molecular formula C6H5ClOS and a molecular weight of 160.62 g/mol. This compound serves as a valuable intermediate in organic synthesis, particularly within the pharmaceutical and agrochemical sectors. Its unique structure, featuring a thiophene ring with both a chlorine atom and an acetyl group, allows for diverse chemical transformations.
- IUPAC
- 5-Chloro-2-thienyl methyl ketone
- Synonyms
- 5-Chloro-2-acetylthiophene5-Chloro-2-thienyl methyl ketone

Pharmaceutical Intermediate
2-Acetyl-5-chlorothiophene is utilised in the synthesis of various active pharmaceutical ingredients (APIs). Its structure provides a versatile scaffold for developing novel therapeutic agents.
Agrochemical Synthesis
The compound acts as a key building block in the development of new agrochemicals, contributing to the creation of advanced crop protection agents.
Organic Synthesis Reagent
As a functionalised thiophene derivative, it is employed in complex organic synthesis pathways for creating specialised molecules and materials.
| Molecular weight | 160.62 |
|---|---|
| Empirical formula | C6H5ClOS |
| Assay | 99% |
| Boiling point | 117-118 °C/17 mmHg(lit.) |
| Melting point | 46-49 °C(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Flash point | 108 °C / 226.4 °F |
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Acetyl-5-chlorothiophene used for?
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2-Acetyl-5-chlorothiophene is primarily used as a building block in organic synthesis, particularly for the development of pharmaceutical intermediates and agrochemicals.
What are the CAS number and formula for 2-Acetyl-5-chlorothiophene?
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The CAS number for 2-Acetyl-5-chlorothiophene is 6310-09-4, and its empirical formula is C6H5ClOS.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Acetyl-5-chlorothiophene with a purity of 99%. We do not represent this product as USP, BP, or EP grade.
How should 2-Acetyl-5-chlorothiophene be handled?
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Handling requires appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter should be used. The compound has a flash point of 108 °C (226.4 °F) and is assigned a WGK (Germany) of 3.
How is 2-Acetyl-5-chlorothiophene packed and shipped?
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Tech Serve Solutions, as a specialist global supplier and exporter, ensures appropriate packing and adherence to all shipping regulations for international distribution.
How can I request a quote or sample for 2-Acetyl-5-chlorothiophene?
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Please use the enquiry form on our website or contact our sales team directly to request a quote or a sample of 2-Acetyl-5-chlorothiophene.
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