2-Acetyl-5,5-dimethyl-1,3-cyclohexanedione
2-Acetyl-5,5-dimethyl-1,3-cyclohexanedione (CAS: 1755-15-3), with a molecular weight of 182.22 g/mol, is a versatile organic compound. It is recognised for its utility as a protecting and derivatizing reagent, particularly in peptide chemistry and organic synthesis. This compound plays a role in chemical biology research, enabling the protection and modification of amine groups during complex syntheses.
- IUPAC
- 2-Acetyldimedone,Dde
- Synonyms
- 1755-15-3C10H14O32-AcetyldimedoneDde

Amine Protection
This reagent is employed to protect amine functionalities during multi-step organic syntheses. Its specific structure allows for selective introduction and removal, preserving the amine group from unwanted reactions.
Peptide Synthesis
In peptide chemistry, it serves as a valuable tool for the derivatization and protection of amino acids or peptide fragments. This facilitates controlled chain elongation and modification in the synthesis of peptides.
Organic Synthesis
2-Acetyl-5,5-dimethyl-1,3-cyclohexanedione is utilized as a building block or reagent in various organic synthesis pathways. It contributes to the construction of complex molecular architectures.
Chemical Biology Research
The compound finds application in chemical biology, where it can be used to modify biomolecules or as a tool for probing biological pathways. Its role in amine protection is relevant for studying protein interactions.
| Molecular weight | 182.22 |
|---|---|
| Empirical formula | C10H14O3 |
| Assay | ≥98.0% (HPLC) |
| Melting point | 36-40 °C |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Acetyl-5,5-dimethyl-1,3-cyclohexanedione used for?
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2-Acetyl-5,5-dimethyl-1,3-cyclohexanedione is primarily used as a protecting and derivatizing reagent in organic synthesis, particularly in peptide chemistry and for amine protection in chemical biology.
What are the CAS number and formula for 2-Acetyl-5,5-dimethyl-1,3-cyclohexanedione?
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The CAS number is 1755-15-3 and the empirical formula is C10H14O3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this chemical with a minimum assay of ≥98.0% (HPLC). TSS does not represent this product as USP, BP, EP or other pharmacopoeial grades unless explicitly stated.
How should 2-Acetyl-5,5-dimethyl-1,3-cyclohexanedione be handled safely?
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This compound is a Warning substance that causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Handle with a dust mask type N95, eyeshields, and gloves in a well-ventilated area. Avoid breathing dust. In case of contact with eyes, rinse cautiously with water for several minutes.
Is this product available for export?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals and laboratory reagents.
How can I request a sample or quote?
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To request a sample or a quotation, please contact our sales team through the website or by phone, providing the product name and CAS number.
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