2-Acetyl-5-iodothiophene
2-Acetyl-5-iodothiophene (CAS: 30955-94-3; C6H5IOS) is a halogenated heterocyclic compound with a molecular weight of 252.07 g/mol. This thiophene derivative serves as a valuable building block in organic synthesis. It is primarily utilised in the development of novel chemical entities and complex organic molecules, particularly within research and development settings for pharmaceuticals and materials science. Its structure offers versatile reactivity for further chemical transformations.

Organic Synthesis Intermediate
2-Acetyl-5-iodothiophene is a key intermediate for introducing the acetylthiophene moiety into more complex molecular structures. Its iodo-substituent is amenable to various cross-coupling reactions, facilitating carbon-carbon and carbon-heteroatom bond formation.
Pharmaceutical Research
This compound is employed in the synthesis of potential drug candidates and heterocyclic scaffolds investigated for biological activity. Its thiophene core is present in several known pharmaceutical agents.
Materials Science
As a functionalised heterocycle, it can be a precursor for synthesising organic electronic materials, polymers, or dyes where specific electronic and optical properties are desired.
| Molecular weight | 252.07 |
|---|---|
| Empirical formula | C6H5IOS |
| Assay | 97% |
| Melting point | 130-134 °C(lit.) |


Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H334May cause allergy or asthma symptoms if inhaled
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
- P342
| Protective equipment | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 36/37/38-42/43 |
| Safety statements (S) | 22-26-36/37-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Acetyl-5-iodothiophene used for?
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2-Acetyl-5-iodothiophene (CAS: 30955-94-3) is primarily used as a building block in organic synthesis, particularly in pharmaceutical research and materials science for creating more complex molecules.
What are the CAS number and formula for 2-Acetyl-5-iodothiophene?
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The CAS number for 2-Acetyl-5-iodothiophene is 30955-94-3, and its molecular formula is C6H5IOS.
What grade and purity does Tech Serve Solutions supply for 2-Acetyl-5-iodothiophene?
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Tech Serve Solutions supplies 2-Acetyl-5-iodothiophene with an assay of 97%. We do not represent this product as USP, EP, BP or pharmacopoeia grade.
How should 2-Acetyl-5-iodothiophene be handled safely?
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2-Acetyl-5-iodothiophene is classified as Danger. It causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335), and allergy or asthma symptoms or breathing difficulties if inhaled (H334). Use a dust mask type N95 (US), together with eyeshields, face shields, and gloves. Ensure adequate ventilation, and avoid breathing dust. Use in accordance with the precautionary statements (P261, P305 + P351 + P338, P342 + P311).
Is 2-Acetyl-5-iodothiophene a controlled substance?
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The provided data does not indicate that 2-Acetyl-5-iodothiophene is a controlled substance.
How is 2-Acetyl-5-iodothiophene packed and exported?
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Tech Serve Solutions, as a specialist global supplier and exporter, ensures appropriate packaging for the safe transport and export of 2-Acetyl-5-iodothiophene, adhering to international shipping regulations.
How can I request a quote or sample for 2-Acetyl-5-iodothiophene?
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To request a quote or sample for 2-Acetyl-5-iodothiophene, please contact our sales team via the details provided on the Tech Serve Solutions website.
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