2-Acetyl-5-bromothiophene
2-Acetyl-5-bromothiophene (CAS: 5370-25-2) is a valuable halogenated heterocyclic building block with the molecular formula C6H5BrOS and a molecular weight of 205.07 g/mol. Its structure, featuring a thiophene ring substituted with bromine and an acetyl group, makes it a versatile intermediate in organic synthesis. This compound is primarily utilised in chemical synthesis for the creation of more complex molecules, particularly within the pharmaceutical and materials science sectors.
- IUPAC
- 5-Bromo-2-thienyl methyl ketone
- Synonyms
- 5-Bromo-2-thienyl methyl ketone5-Bromo-2-acetylthiopheneMethyl 5-bromothien-2-yl ketone

Organic Synthesis Intermediate
Serves as a key building block in multi-step organic syntheses, enabling the introduction of a brominated acetylthiophene moiety into target molecules. Its reactivity allows for various transformations, including cross-coupling reactions and further functionalisation.
Pharmaceutical Research
Used in the development of novel pharmaceutical compounds. The thiophene scaffold is present in many biologically active molecules, and this derivative can be employed to synthesise potential drug candidates or intermediates.
Materials Science
Applicable in the synthesis of advanced materials, such as organic semiconductors or conductive polymers, where the electronic properties of the thiophene ring are advantageous. The bromine atom provides a handle for further polymerisation or functionalisation.
| Molecular weight | 205.07 |
|---|---|
| Empirical formula | C6H5BrOS |
| Assay | 99% |
| Boiling point | 103 °C/4 mmHg(lit.) |
| Melting point | 94-96 °C(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Acetyl-5-bromothiophene primarily used for?
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2-Acetyl-5-bromothiophene (CAS: 5370-25-2) is predominantly used as a building block in organic synthesis for the creation of more complex molecules, especially in pharmaceutical research and materials science.
What are the CAS number and molecular formula for 2-Acetyl-5-bromothiophene?
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The CAS number for 2-Acetyl-5-bromothiophene is 5370-25-2, and its empirical formula is C6H5BrOS.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Acetyl-5-bromothiophene with a minimum purity of 99% (Assay). This product is supplied for research and laboratory use and is not represented as USP, BP, EP, or other pharmacopoeia grades.
What are the safety and handling precautions for 2-Acetyl-5-bromothiophene?
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2-Acetyl-5-bromothiophene is classified with GHS hazards and should be handled with appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. Always consult the Safety Data Sheet (SDS) for comprehensive handling information.
How is 2-Acetyl-5-bromothiophene packed, shipped, and exported?
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Products are carefully packed according to international shipping regulations and available in various pack sizes to meet diverse research and production needs. Tech Serve Solutions is a global exporter, ensuring reliable supply worldwide.
How can I request a quote or sample for 2-Acetyl-5-bromothiophene?
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To request a quote or a sample, please use the 'Request a Quote' or 'Request a Sample' buttons on the product page, or contact our sales team directly. We aim to respond promptly to all enquiries.
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