2-Acetyl-4-methylthiophene
2-Acetyl-4-methylthiophene (CAS: 13679-73-7), a heterocyclic organic compound with the formula C7H8OS and a molecular weight of 140.20 g/mol, is a valuable building block in chemical synthesis. It features a thiophene ring substituted with an acetyl group and a methyl group. This compound is primarily utilised in the development of novel organic molecules and serves as an intermediate in various research and development applications within the fine chemical and pharmaceutical sectors.
- IUPAC
- 1-(4-Methyl-2-thienyl)ethanone
- Synonyms
- 1-(4-Methyl-2-thienyl)ethanone

Organic Synthesis Intermediate
2-Acetyl-4-methylthiophene is employed as a key intermediate in the synthesis of more complex organic molecules. Its functional groups, the ketone and the thiophene ring, allow for a variety of chemical transformations.
Heterocyclic Chemistry Research
As a substituted thiophene derivative, this compound is of interest in heterocyclic chemistry research. It can be used to explore new reactions and synthesise novel thiophene-based structures with potential applications.
Pharmaceutical Research
The compound may serve as a building block in the discovery and development of new pharmaceutical agents. Thiophene derivatives are known scaffolds in medicinal chemistry.
| Molecular weight | 140.20 |
|---|---|
| Empirical formula | C7H8OS |
| Assay | 97% |
| Boiling point | 108-109 °C(lit.) |
| Density | 1.224 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.5600(lit.) |

Hazard statements
- H302Harmful if swallowed
- H317May cause an allergic skin reaction
- H319Causes serious eye irritation
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 105 °C / 221 °F |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-36-43 |
| Safety statements (S) | 26-37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Acetyl-4-methylthiophene used for?
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2-Acetyl-4-methylthiophene is primarily used as a building block and intermediate in organic synthesis, particularly in heterocyclic and pharmaceutical research.
What are the CAS number and formula for 2-Acetyl-4-methylthiophene?
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The CAS number is 13679-73-7, and the empirical formula is C7H8OS.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Acetyl-4-methylthiophene with an assay of 97%. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade; it is intended for research and technical use.
What are the primary safety hazards associated with 2-Acetyl-4-methylthiophene?
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2-Acetyl-4-methylthiophene is classified with GHS07 symbol and a Warning signal word. It carries hazard statements H302 (Harmful if swallowed), H317 (May cause an allergic skin reaction), and H319 (Causes serious eye irritation). Appropriate personal protective equipment, including eyeshields, gloves, and suitable respiratory protection, should be used.
How is 2-Acetyl-4-methylthiophene shipped and exported?
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Tech Serve Solutions is an experienced global supplier and exporter of fine chemicals, capable of arranging shipment and export of 2-Acetyl-4-methylthiophene in compliance with international regulations.
How can I request a sample or quote for 2-Acetyl-4-methylthiophene?
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To request a sample or a quotation for 2-Acetyl-4-methylthiophene, please contact our sales department through the website or by telephone.
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