3-Fluoropyridine
3-Fluoropyridine (CAS 372-47-4), with the molecular formula FC5H4N and a molar mass of 97.09 g/mol, is a valuable fluorinated heterocyclic building block. It is primarily utilised in chemical synthesis, particularly in the preparation of more complex organic molecules. Its applications are centred around its role as a reactive intermediate in research and development within the pharmaceutical and agrochemical sectors.
Synthesis of Boronic Acids and Esters
3-Fluoropyridine serves as a key precursor in the synthesis of 3-halopyridin-4-yl-boronic acids and their corresponding esters. These compounds are important intermediates in cross-coupling reactions.
Fluorinated Heterocycle Intermediate
As a fluorinated pyridine derivative, this compound is integral to the development of novel fluorinated organic molecules. It enables the introduction of a fluorine atom into heterocyclic structures, a common strategy in medicinal chemistry.
Research and Development
Utilised in academic and industrial research laboratories for exploring new synthetic pathways and developing novel compounds with potential biological activity.
| Molecular weight | 97.09 |
|---|---|
| Linear formula | FC5H4N |
| Assay | 99% |
| Boiling point | 107-108 °C(lit.) |
| Density | 1.13 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.472(lit.) |
| Application | 3-Fluoropyridine was used in the synthesis of 3-halopyridin-4-yl-boronic acids and esters1. |
Hazard statements
- H225Highly flammable liquid and vapour
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 13 °C / 55.4 °F |
| Transport (UN / ADR) | UN 1993BF 3 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,Xi |
| Risk statements (R) | 11-36/37/38 |
| Safety statements (S) | 16-26-36/37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3-Fluoropyridine used for?
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3-Fluoropyridine is used as a building block in chemical synthesis, particularly for preparing 3-halopyridin-4-yl-boronic acids and esters, and in the development of novel fluorinated heterocyclic compounds for research.
What is the CAS number and chemical formula for 3-Fluoropyridine?
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The CAS number for 3-Fluoropyridine is 372-47-4, and its chemical formula is FC5H4N.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 3-Fluoropyridine with a minimum purity of 99% (assay). This product is intended for research and chemical synthesis and is not supplied as USP, BP, EP, or pharmaceutical grade.
What are the primary safety concerns when handling 3-Fluoropyridine?
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3-Fluoropyridine is a highly flammable liquid and vapour (H225). It is harmful if inhaled and causes skin (H315) and serious eye irritation (H319). It may also cause respiratory irritation (H335). Appropriate personal protective equipment, including safety glasses, gloves, and respiratory protection, must be used. Handle in a well-ventilated area away from ignition sources.
How is 3-Fluoropyridine shipped and exported?
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3-Fluoropyridine is classified under UN 1993, BF 3, Packing Group II, indicating it is shipped as a flammable liquid. Tech Serve Solutions is a global supplier and exporter experienced in handling and shipping hazardous chemicals worldwide.
How can I request a quote or sample for 3-Fluoropyridine?
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To request a quote or a sample of 3-Fluoropyridine, please contact our sales team through the website or by phone. We will be happy to assist you with your chemical requirements.
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