3-Fluorophthalic anhydride
3-Fluorophthalic anhydride (CAS: 652-39-1, Formula: C8H3FO3) is a fluorinated organic building block with a molecular weight of 166.11 g/mol. This compound functions as a key intermediate in organic synthesis, particularly in the preparation of pharmaceuticals and other fine chemicals. Its structure, featuring both an anhydride and a fluorine substituent on the phthalic acid core, offers unique reactivity for constructing complex molecular architectures.

Pharmaceutical Intermediate
Utilised in the synthesis of substituted benzamides, which have shown potential neuroleptic activity. This highlights its role in the development of new therapeutic agents.
Organic Synthesis Building Block
Serves as a valuable precursor in various organic chemical reactions. Its fluorinated nature and anhydride functionality enable specific chemical transformations for creating novel compounds.
Research and Development
Employed in academic and industrial research laboratories for exploring new chemical pathways and developing innovative materials and molecules.
| Molecular weight | 166.11 |
|---|---|
| Empirical formula | C8H3FO3 |
| Assay | 95% |
| Application | Used in the preparation of substituted benzamides with potential neuroleptic activity.1 |
| Melting point | 158-161 °C(lit.) |

Hazard statements
- H315Causes skin irritation
- H317May cause an allergic skin reaction
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 36/37/38-42/43 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3-Fluorophthalic anhydride used for?
+
3-Fluorophthalic anhydride is primarily used as a building block in organic synthesis, including the preparation of substituted benzamides with potential neuroleptic activity.
What is the CAS number and chemical formula for 3-Fluorophthalic anhydride?
+
The CAS number is 652-39-1 and the chemical formula is C8H3FO3.
What grade and purity does Tech Serve Solutions supply for 3-Fluorophthalic anhydride?
+
Tech Serve Solutions supplies 3-Fluorophthalic anhydride with an assay of 95%. We do not represent this product as USP, BP, or EP grade.
How should 3-Fluorophthalic anhydride be handled safely?
+
Handle with appropriate personal protective equipment including a dust mask (type N95 or equivalent), eyeshields, face shields, and gloves. Avoid breathing dust. This compound is an irritant to the respiratory system, skin, and eyes.
Can Tech Serve Solutions export 3-Fluorophthalic anhydride?
+
Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals and can export 3-Fluorophthalic anhydride.
How can I request a quote or sample for 3-Fluorophthalic anhydride?
+
Please contact our sales team through our website to request a quote or sample of 3-Fluorophthalic anhydride.
▶ Related products

1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis

1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more

3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis

3-Methyl-1,5-pentanediol
Chemical Synthesis

3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis