4-Hydroxy-3-methoxybenzyl alcohol
4-Hydroxy-3-methoxybenzyl alcohol (CAS 498-00-0), with the molecular formula HOC6H3(OCH3)CH2OH and a molecular weight of 154.16, is a bifunctional organic compound. This aromatic alcohol, also known as vanillyl alcohol, features both a hydroxyl group and a primary alcohol function, making it a versatile building block in chemical synthesis. It serves as a key intermediate in the preparation of various organic compounds and is utilized in research and development settings.
- IUPAC
- Vanillyl alcohol
- Synonyms
- Vanillyl alcohol

Organic Synthesis Intermediate
4-Hydroxy-3-methoxybenzyl alcohol is employed as a fundamental building block in the synthesis of more complex organic molecules. Its dual functionality allows for selective reactions at either the phenolic hydroxyl or the benzylic alcohol group, enabling diverse synthetic pathways.
Chemical Biology Research
As a derivative of vanillin, this compound can be used in studies related to natural products and their biological activities. It may serve as a starting material for synthesizing probes or modified analogues for biochemical investigations.
Linker and Crosslinker Precursor
The bifunctional nature of 4-Hydroxy-3-methoxybenzyl alcohol makes it suitable for derivatization into linkers or crosslinking agents. These can be used in material science or bioconjugation chemistry to connect different molecular entities.
| Molecular weight | 154.16 |
|---|---|
| Linear formula | HOC6H3(OCH3)CH2OH |
| Assay | ≥98.0% (GC) |
| Melting point | 108-112 °C110-117 °C(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
| Ignition residue | ~1% |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Hydroxy-3-methoxybenzyl alcohol primarily used for?
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4-Hydroxy-3-methoxybenzyl alcohol is primarily used as an intermediate in organic synthesis and in chemical biology research. It serves as a versatile building block due to its bifunctional nature.
What are the CAS number and chemical formula for 4-Hydroxy-3-methoxybenzyl alcohol?
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The CAS number for 4-Hydroxy-3-methoxybenzyl alcohol is 498-00-0, and its chemical formula is HOC6H3(OCH3)CH2OH.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-Hydroxy-3-methoxybenzyl alcohol with an assay of ≥98.0% (GC). This product is intended for research and laboratory use and is not represented as USP, BP, EP, or any other pharmacopoeia grade.
How should 4-Hydroxy-3-methoxybenzyl alcohol be handled safely?
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4-Hydroxy-3-methoxybenzyl alcohol is classified with GHS07, a Warning signal word, and carries hazard statements H315 (Causes skin irritation), H319 (Causes serious eye irritation), and H335 (May cause respiratory irritation). Safe handling requires wearing a dust mask type N95, eyeshields, and gloves. Use in a well-ventilated area and avoid inhaling dust. Ensure prompt cleanup if spilled. Refer to the Safety Data Sheet for comprehensive handling information.
Is 4-Hydroxy-3-methoxybenzyl alcohol a controlled substance?
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Based on the provided data, 4-Hydroxy-3-methoxybenzyl alcohol is not listed as a controlled substance.
How is 4-Hydroxy-3-methoxybenzyl alcohol packed and shipped?
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Tech Serve Solutions packages and exports 4-Hydroxy-3-methoxybenzyl alcohol in compliance with international shipping regulations for chemicals. Specific packaging details can be provided upon request.
How can I request a sample or quote for 4-Hydroxy-3-methoxybenzyl alcohol?
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To request a sample or a quotation for 4-Hydroxy-3-methoxybenzyl alcohol, please contact our sales department through the website or by phone, providing your specific requirements.
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