4-Hydroxy-3-methoxyphenylacetonitrile
4-Hydroxy-3-methoxyphenylacetonitrile (CAS: 4468-59-1) is a chemical compound with the molecular formula HOC₆H₃(OCH₃)CH₂CN and a molecular weight of 163.17 g/mol. It serves as a valuable building block in organic synthesis. This nitrile compound is characterised by its specific aromatic structure, making it useful in the creation of more complex molecules within chemical research and development settings. Tech Serve Solutions supplies this compound for laboratory and industrial applications.
- IUPAC
- Homovanillonitrile
- Synonyms
- Homovanillonitrile

Organic Synthesis Intermediate
Utilised as a key intermediate in the synthesis of various organic compounds. Its functional groups allow for diverse chemical transformations, contributing to the development of novel molecules.
Chemical Research and Development
Employed in R&D laboratories for the exploration of new chemical pathways and the creation of fine chemicals. Its structure is suitable for reactions leading to pharmaceuticals and speciality chemicals.
Building Block for Complex Molecules
Serves as a fundamental building block in multi-step synthetic processes. The presence of the nitrile and phenolic ether functionalities provides reactive sites for elaboration.
| Molecular weight | 163.17 |
|---|---|
| Linear formula | HOC6H3(OCH3)CH2CN |
| Assay | 99% |
| Boiling point | 135-145 °C/2 mmHg(lit.) |
| Melting point | 56-57 °C(lit.) |

Hazard statements
- H302Harmful if swallowed
- H312Harmful in contact with skin
- H315Causes skin irritation
- H319Causes serious eye irritation
- H332Harmful if inhaled
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 20/21/22-36/37/38 |
| Safety statements (S) | 26-37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Hydroxy-3-methoxyphenylacetonitrile used for?
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4-Hydroxy-3-methoxyphenylacetonitrile is primarily used as a building block in organic synthesis and in chemical research and development for creating more complex molecules.
What is the CAS number and formula for 4-Hydroxy-3-methoxyphenylacetonitrile?
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The CAS number is 4468-59-1 and the linear formula is HOC₆H₃(OCH₃)CH₂CN.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-Hydroxy-3-methoxyphenylacetonitrile with an assay of 99%. TSS does not represent this product as USP, BP, EP, or other pharmacopoeia grades.
How should 4-Hydroxy-3-methoxyphenylacetonitrile be handled?
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This compound is classified as harmful if swallowed, in contact with skin, or if inhaled, and causes skin and eye irritation, and respiratory irritation. Handle with appropriate personal protective equipment including a dust mask (type N95 US), eyeshields, and gloves in a well-ventilated area, and avoid breathing dust.
Is 4-Hydroxy-3-methoxyphenylacetonitrile exported by Tech Serve Solutions?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including 4-Hydroxy-3-methoxyphenylacetonitrile.
How can I request a quote or sample for 4-Hydroxy-3-methoxyphenylacetonitrile?
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Please contact our sales team through the website to request a quote or a sample for 4-Hydroxy-3-methoxyphenylacetonitrile.
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