4-Hydroxy-3-methoxyphenylboronic acid pinacol ester
4-Hydroxy-3-methoxyphenylboronic acid pinacol ester (CAS: 269410-22-2), with the molecular formula C13H19BO4 and a molecular weight of 250.10, is a valuable aryl boronate ester. It serves as a versatile building block in organic synthesis, particularly in cross-coupling reactions. This compound finds application in the development of complex molecules within the pharmaceutical and materials science sectors, owing to its role in constructing carbon-carbon bonds.
- IUPAC
- 2-Methoxy-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol,4-Hydroxy-3-methoxyphenylboronic acid, pinacol cyclic ester
- Synonyms
- 2-Methoxy-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol4-Hydroxy-3-methoxyphenylboronic acid, pinacol cyclic ester
Suzuki-Miyaura Coupling Reactions
This boronate ester is a key reagent in Suzuki-Miyaura coupling, enabling the formation of biaryl compounds by reacting with aryl or vinyl halides. It is instrumental in the synthesis of various complex organic molecules.
Pharmaceutical Intermediate Synthesis
Used in the multi-step synthesis of active pharmaceutical ingredients (APIs) and drug discovery programs. Its functional groups allow for precise molecular modifications and the construction of novel therapeutic agents.
Materials Science Research
Applicable in the development of novel organic materials, such as organic light-emitting diodes (OLEDs) or advanced polymers. The compound facilitates the creation of conjugated systems with tailored electronic properties.
Agrochemical Development
Can be employed in the synthesis of new agrochemical compounds, contributing to the development of more effective and selective pesticides or herbicides.
| Molecular weight | 250.10 |
|---|---|
| Empirical formula | C13H19BO4 |
| Assay | 98% |
| Melting point | 105-109 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Hydroxy-3-methoxyphenylboronic acid pinacol ester used for?
+
This compound is primarily used as a building block in organic synthesis, particularly in Suzuki-Miyaura cross-coupling reactions for the construction of biaryl compounds, and in the synthesis of pharmaceutical intermediates and advanced materials.
What is the CAS number and chemical formula?
+
The CAS number is 269410-22-2 and the chemical formula is C13H19BO4.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies this product at an assay of 98%. This is a technical/research grade material and is not represented as USP, BP, EP, or any other pharmacopoeia grade.
How should 4-Hydroxy-3-methoxyphenylboronic acid pinacol ester be handled safely?
+
The compound is classified as an irritant to the skin, eyes, and respiratory tract (H315, H319, H335). Handle with appropriate personal protective equipment, including a dust mask (N95), eyeshields, and gloves. Ensure adequate ventilation and avoid dust formation.
Is this chemical a controlled substance?
+
The provided data does not indicate that 4-Hydroxy-3-methoxyphenylboronic acid pinacol ester is a controlled substance.
How is this chemical shipped and exported?
+
Tech Serve Solutions is a global supplier and exporter of fine chemicals. Specific packaging and shipping details will be provided upon inquiry, adhering to all international regulations for chemical transport.
How can I request a sample or quote?
+
To request a sample or a quote for 4-Hydroxy-3-methoxyphenylboronic acid pinacol ester, please contact our sales team through the website or via direct inquiry, providing your specific requirements.
▶ Related products
1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis
1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis