3-Formyl-1H-indole-5-carbonitrile
3-Formyl-1H-indole-5-carbonitrile (CAS: 17380-18-6; Formula: C10H6N2O; Molar Mass: 170.17 g/mol) is a fine chemical intermediate. This indole derivative, characterised by its formyl and nitrile functionalities, serves as a key building block in organic synthesis. It is employed in the development of potential pharmaceuticals, including anticancer immunomodulators, antifungal agents, and compounds targeting neurological disorders. Its applications are primarily within chemical research and development laboratories.
- IUPAC
- 3-Formyl-5-cyano-1H-indole,5-Cyanoindole-3-carboxaldehyde
- Synonyms
- 5-Cyanoindole-3-carboxaldehyde3-Formyl-5-cyano-1H-indole
Anticancer Immunomodulator Precursor
Utilised as a reactant in the synthesis of tryptophan dioxygenase inhibitors, which are investigated for their potential as anticancer immunomodulators.
Antifungal Agent Synthesis
Serves as a reactant in the enantioselective preparation of novel antifungal agents.
BACE-1 Inhibitor Development
A reactant in the synthesis of indole- and 7-azaindole-1,3-dicarboxamide hydroxyethylamine inhibitors of BACE-1.
Antibacterial Agent Intermediate
Employed in the preparation of indolyl alkenes via microwave-enhanced Knoevenagel condensation, investigated for antibacterial properties.
Antitumor Agent Research
A reactant for the preparation of indolecarboxamide derivatives that are studied for their antitumor activities.
Selective Serotonin Reuptake Inhibitor Synthesis
Used as a reactant in the synthetic pathways for selective serotonin reuptake inhibitors (SSRIs).
| Molecular weight | 170.17 |
|---|---|
| Empirical formula | C10H6N2O |
| Assay | 97% |
| Application | • Reactant for synthesis of tryptophan dioxygenase inhibitors as potential anticancer immunomodulators1• Reactant for enantioselective preparation of antifungal agents2• Reactant for synthesis of indole- and 7-azaindole-1,3-dicarboxamide hydroxyethylamine inhibitors of BACE-13• Reactant for preparation of indolyl alkenes from microwave-enhanced Knoevenagel condensation as antibacterial agents4• Reactant for preparation of indolecarboxamide derivatives as antitumor agents5• Reactant for synthesis of a selective serotonin reuptake inhibitor6 |
| Melting point | 248-253 °C |
Hazard statements
- H302Harmful if swallowed
- H312Harmful in contact with skin
- H315Causes skin irritation
- H317May cause an allergic skin reaction
- H319Causes serious eye irritation
- H332Harmful if inhaled
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 20/21/22-36/37/38-43 |
| Safety statements (S) | 26-36/37 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3-Formyl-1H-indole-5-carbonitrile used for?
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3-Formyl-1H-indole-5-carbonitrile is used as a reactant and building block in organic synthesis, particularly for the development of potential pharmaceuticals such as anticancer immunomodulators, antifungal agents, BACE-1 inhibitors, antibacterial agents, and selective serotonin reuptake inhibitors.
What is the CAS number and formula for 3-Formyl-1H-indole-5-carbonitrile?
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The CAS number is 17380-18-6, and the empirical formula is C10H6N2O.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 3-Formyl-1H-indole-5-carbonitrile with a minimum assay of 97%. This product is intended for research and chemical synthesis purposes and is not supplied as USP, BP, EP, or any other pharmacopoeial grade.
How should 3-Formyl-1H-indole-5-carbonitrile be handled safely?
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Handling requires appropriate personal protective equipment, including a dust mask (type N95 or equivalent), eyeshields, face shields, and gloves. It is classified as a Warning substance with hazards including harmful if swallowed, in contact with skin, or if inhaled; causes skin irritation, serious eye irritation, and may cause an allergic skin reaction or respiratory irritation. Consult the Safety Data Sheet for full details.
How is this chemical packed, shipped, or exported?
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Tech Serve Solutions packs and exports chemicals in compliance with all relevant international shipping regulations to ensure safe and secure delivery to customers worldwide.
How can I request a sample or quote for 3-Formyl-1H-indole-5-carbonitrile?
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To request a sample or obtain a quotation, please visit the Tech Serve Solutions website and use the contact form or product inquiry feature, referencing the product name and CAS number.
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