3-Fluorophenylboronic acid
3-Fluorophenylboronic acid (CAS 768-35-4), with the molecular formula FC6H4B(OH)2 and a molecular weight of 139.92 g/mol, is a crucial organoboron compound. It serves as a valuable building block in organic synthesis, particularly in palladium-catalyzed cross-coupling reactions. Its applications span the creation of complex organic molecules, including liquid crystals and biologically active compounds.
- IUPAC
- (3-Fluorophenyl-1-yl)boronic acid,3-Fluorobenzeneboronic acid,m-fluoro-Benzeneboronic acid,m-Fluorophenylboronic acid
- Synonyms
- 3-Fluorobenzeneboronic acidm-Fluorobenzeneboronic acidm-Fluoro-benzeneboronic acid(3-Fluorophenyl-1-yl)boronic acid
Synthesis of Liquid Crystalline Materials
3-Fluorophenylboronic acid has been utilised in the synthesis of novel liquid crystalline fluorobiphenylcyclohexenes and difluoroterphenyls through palladium-catalyzed cross-coupling reactions.
Preparation of Leukotriene Receptor Agonists
This compound is employed in the synthesis of ortho-phenylphenols which have demonstrated potency as leukotriene B4 receptor agonists.
Organic Synthesis Building Block
As an aryl boronic acid derivative, it is a versatile reagent in Suzuki-Miyaura cross-coupling reactions for forming carbon-carbon bonds in complex molecule construction.
| Molecular weight | 139.92 |
|---|---|
| Linear formula | FC6H4B(OH)2 |
| Assay | ≥95.0% |
| Application | Recently used to make novel liquid crystalline fluorobiphenylcyclohexenes1 and difluoroterphenyls2 by palladium-catalyzed cross-couplings also used in the synthesis of o-phenylphenols as potent leukotriene B4 receptor agonists.3 |
| Melting point | 214-218 °C(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3-Fluorophenylboronic acid used for?
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3-Fluorophenylboronic acid is used as a building block in organic synthesis, including the preparation of liquid crystalline materials and biologically active compounds like leukotriene B4 receptor agonists, primarily via palladium-catalyzed cross-coupling reactions.
What are the CAS number and chemical formula for 3-Fluorophenylboronic acid?
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The CAS number for 3-Fluorophenylboronic acid is 768-35-4, and its linear chemical formula is FC6H4B(OH)2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 3-Fluorophenylboronic acid with an assay of ≥95.0%. We do not represent this product as meeting any pharmacopoeial standards (e.g., USP, BP, EP) unless explicitly stated.
What are the safety and handling requirements for 3-Fluorophenylboronic acid?
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Handling 3-Fluorophenylboronic acid requires appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter should be used. It has a GHS classification indicating specific hazards.
How is 3-Fluorophenylboronic acid packed, shipped, and exported?
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Tech Serve Solutions ensures appropriate packaging for safe transport and export of 3-Fluorophenylboronic acid, adhering to international shipping regulations for chemicals.
How can I request a sample or quote for 3-Fluorophenylboronic acid?
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To request a sample or obtain a quotation for 3-Fluorophenylboronic acid, please contact our sales department via the website or direct inquiry.
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