3-(Difluoromethyl)pyridine
3-(Difluoromethyl)pyridine (CAS: 76541-44-1, C6H5F2N) is a fluorinated pyridine derivative with a molecular weight of 129.11 g/mol. This building block is valuable in organic synthesis, particularly for introducing the difluoromethyl group into target molecules. Its pyridine core offers diverse reactivity, making it a useful intermediate in the development of novel chemical entities across various research fields.
Pharmaceutical Intermediate
Used in the synthesis of active pharmaceutical ingredients (APIs), leveraging the unique properties of the difluoromethylpyridine moiety to influence drug efficacy and pharmacokinetics.
Agrochemical Synthesis
Serves as a key building block for developing new pesticides, herbicides, and fungicides, where fluorinated heterocycles can enhance biological activity and stability.
Materials Science
Incorporated into the design of advanced materials, such as polymers or functional dyes, where its specific electronic and structural characteristics can be beneficial.
Organic Synthesis Reagent
A versatile reagent for introducing the difluoromethylpyridine fragment into complex organic structures, enabling access to novel chemical space for research and development.
| Molecular weight | 129.11 |
|---|---|
| Empirical formula | C6H5F2N |
| Assay | 97% |
| Density | 1.242 g/mL at 25 °C |
| Refractive index | n20/D 1.462 |
Hazard statements
- H226Flammable liquid and vapour
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Flash point | 54 °C / 129.2 °F |
|---|---|
| Transport (UN / ADR) | UN 1993C 3 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 10-36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3-(Difluoromethyl)pyridine used for?
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3-(Difluoromethyl)pyridine is primarily used as a building block in organic synthesis, particularly in the development of pharmaceuticals, agrochemicals, and advanced materials, due to the presence of the difluoromethyl group and the pyridine core.
What is the CAS number and formula for 3-(Difluoromethyl)pyridine?
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The CAS number for 3-(Difluoromethyl)pyridine is 76541-44-1, and its empirical formula is C6H5F2N.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 3-(Difluoromethyl)pyridine with an assay of 97%. We do not represent this product as USP, BP, EP, or other pharmacopoeia grades.
How should 3-(Difluoromethyl)pyridine be handled safely?
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3-(Difluoromethyl)pyridine is a flammable liquid and vapour (H226) and causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Handle in a well-ventilated area, away from heat and ignition sources, wearing appropriate personal protective equipment.
Is 3-(Difluoromethyl)pyridine suitable for export?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including 3-(Difluoromethyl)pyridine, adhering to international shipping regulations (UN 1993, Class 3, PG III).
How can I request a sample or quote for 3-(Difluoromethyl)pyridine?
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Please contact our sales team via the website or email to request a sample or a quotation for 3-(Difluoromethyl)pyridine.
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