3-(Difluoromethoxy)nitrobenzene
3-(Difluoromethoxy)nitrobenzene (CAS: 22236-07-3) is an organic compound with the molecular formula F2CHOC6H4NO2 and a molecular weight of 189.12 g/mol. This nitro compound serves as a valuable building block in chemical synthesis, particularly for introducing the difluoromethoxy group into organic molecules. It is commonly utilised in the development of pharmaceuticals and agrochemicals, where this functional group can impart unique properties.
Organic Synthesis Intermediate
Utilised as a key intermediate in the synthesis of complex organic molecules. Its structure allows for further chemical modifications, making it useful in the creation of novel compounds.
Pharmaceutical Development
A building block in the research and development of new pharmaceutical agents. The difluoromethoxy moiety can influence drug metabolism, lipophilicity, and binding affinity.
Agrochemical Research
Employed in the synthesis of potential new agrochemicals. The difluoromethoxy group can enhance the efficacy and stability of pesticides and herbicides.
| Molecular weight | 189.12 |
|---|---|
| Linear formula | F2CHOC6H4NO2 |
| Assay | 97% |
| Boiling point | 240-242 °C(lit.) |
| Density | 1.391 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.502(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 110 °C / 230 °F |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3-(Difluoromethoxy)nitrobenzene used for?
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3-(Difluoromethoxy)nitrobenzene is primarily used as a building block in organic synthesis, particularly in the development of pharmaceuticals and agrochemicals.
What is the CAS number and chemical formula for 3-(Difluoromethoxy)nitrobenzene?
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The CAS number is 22236-07-3 and the linear chemical formula is F2CHOC6H4NO2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 3-(Difluoromethoxy)nitrobenzene with a minimum assay of 97%. This product is suitable for research and synthesis purposes; TSS does not represent it as USP, BP, or EP grade.
What are the primary safety concerns when handling 3-(Difluoromethoxy)nitrobenzene?
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This compound is classified with a Warning signal word and carries hazard statements H315 (causes skin irritation), H319 (causes serious eye irritation), and H335 (may cause respiratory irritation). Appropriate personal protective equipment, including eyeshields and gloves, should be worn, and handling should occur in a well-ventilated area or fume hood.
How is 3-(Difluoromethoxy)nitrobenzene typically packed and shipped?
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As a global supplier and exporter, Tech Serve Solutions ensures that 3-(Difluoromethoxy)nitrobenzene is packed and shipped in compliance with all relevant international regulations for chemical transport.
How can I request a quote or sample for 3-(Difluoromethoxy)nitrobenzene?
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To request a quote or sample, please use the contact form on our website or contact our sales department directly, referencing the product name and CAS number 22236-07-3.
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