3,5-Difluoropyridine
3,5-Difluoropyridine (CAS 71902-33-5) is a halogenated heterocyclic compound with the molecular formula C5H3F2N and a molecular weight of 115.08 g/mol. This fluorinated building block is primarily utilised in chemical synthesis, particularly in the development of novel pharmaceutical intermediates and agrochemicals. Its unique difluoro-substitution pattern offers distinct reactivity for constructing complex molecular architectures. Available from Tech Serve Solutions with a purity of 97%.
- Synonyms
- C5H3F2N3,5-Difluoropyridine

Pharmaceutical Intermediate Synthesis
3,5-Difluoropyridine serves as a key building block in the synthesis of advanced pharmaceutical compounds. Its fluorinated pyridine core can be incorporated into drug candidates to modify pharmacokinetic properties such as metabolic stability and lipophilicity.
Agrochemical Development
This compound is employed in the creation of novel agrochemicals. The incorporation of fluorine atoms can enhance the efficacy and environmental profile of pesticides and herbicides by influencing their biological activity and degradation pathways.
Materials Science Research
As a fluorinated heterocyclic, 3,5-Difluoropyridine may find applications in materials science, contributing to the synthesis of specialised polymers or electronic materials where the unique electronic and physical properties imparted by fluorine are advantageous.
| Molecular weight | 115.08 |
|---|---|
| Empirical formula | C5H3F2N |
| Assay | 97% |
| Density | 1.256 g/mL at 25 °C |
| Refractive index | n20/D 1.444 |



Hazard statements
- H225Highly flammable liquid and vapour
- H302Harmful if swallowed
- H312Harmful in contact with skin
- H315Causes skin irritation
- H319Causes serious eye irritation
- H332Harmful if inhaled
- H335May cause respiratory irritation
- H400Very toxic to aquatic life
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P261Avoid breathing dust, fume, gas or vapours
- P273Avoid release to the environment
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 7 °C / 44.6 °F |
| Transport (UN / ADR) | UN 1993BE 3 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,Xn,N |
| Risk statements (R) | 11-20/21/22-36/37/38-50 |
| Safety statements (S) | 26-36/37-61 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3,5-Difluoropyridine used for?
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3,5-Difluoropyridine is primarily used as a building block in chemical synthesis, particularly for the development of pharmaceutical intermediates and agrochemicals.
What is the CAS number and molecular formula for 3,5-Difluoropyridine?
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The CAS number for 3,5-Difluoropyridine is 71902-33-5, and its molecular formula is C5H3F2N.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 3,5-Difluoropyridine with an assay of 97%. We do not represent this product as USP, BP, or EP grade.
How should 3,5-Difluoropyridine be handled safely?
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3,5-Difluoropyridine is flammable and harmful if swallowed, inhaled, or in contact with skin. It can cause skin, eye, and respiratory irritation. Handling requires appropriate personal protective equipment, including eyeshields, gloves, and respiratory protection. Ensure adequate ventilation and avoid ignition sources. Refer to the Safety Data Sheet for full details.
Is 3,5-Difluoropyridine a controlled substance?
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The provided data does not indicate that 3,5-Difluoropyridine is a controlled substance.
How is 3,5-Difluoropyridine packed, shipped, and exported?
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3,5-Difluoropyridine is packed and shipped according to relevant regulations for hazardous materials, including UN 1993 classification. Tech Serve Solutions is an experienced global exporter.
How can I request a sample or quote for 3,5-Difluoropyridine?
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To request a sample or a quote for 3,5-Difluoropyridine, please contact the Tech Serve Solutions sales team via our website or direct contact details.
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