3,5-Difluorophenylzinc bromide solution
3,5-Difluorophenylzinc bromide solution (CAS: 307531-85-7, F2C6H3ZnBr) is an organozinc halide supplied by Tech Serve Solutions at a concentration of 0.5 M in THF. With a molecular weight of 258.38 g/mol, this reagent is a valuable building block in organic synthesis, particularly for the formation of carbon-carbon bonds through cross-coupling reactions. Its utility is primarily in advanced chemical synthesis and research applications, offering a reliable source of the 3,5-difluorophenyl moiety.
- Synonyms
- F2C6H3ZnBr
Cross-Coupling Reactions
Serves as a nucleophilic coupling partner in transition metal-catalysed cross-coupling reactions, such as Negishi couplings, for the synthesis of complex organic molecules containing the 3,5-difluorophenyl group.
Organometallic Synthesis
As an organozinc reagent, it is instrumental in introducing the 3,5-difluorophenyl group into various substrates, facilitating the construction of novel chemical entities.
Pharmaceutical Intermediate Synthesis
Used in the multi-step synthesis of active pharmaceutical ingredients (APIs) where the difluorophenyl moiety is a key structural element.
Materials Science
Enables the development of new organic materials by incorporating the specific electronic and structural properties conferred by the 3,5-difluorophenyl unit.
| Molecular weight | 258.38 |
|---|---|
| Linear formula | F2C6H3ZnBr |
| Boiling point | 65 °C |
| Density | 0.992 g/mL at 25 °C |
| Concentration | 0.5 M in THF |
| Storage temperature | 2-8°C |
Hazard statements
- H225Highly flammable liquid and vapour
- H319Causes serious eye irritation
- H335May cause respiratory irritation
- H351Suspected of causing cancer
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P261Avoid breathing dust, fume, gas or vapours
- P281Use personal protective equipment as required
- P305IF IN EYES
| Flash point | -17 °C / 1.4 °F |
|---|---|
| Transport (UN / ADR) | UN 2056 3 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,Xn |
| Risk statements (R) | 11-19-36/37-40 |
| Safety statements (S) | 16-26-36/37 |
| Supplemental hazards | May form explosive peroxides. |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3,5-Difluorophenylzinc bromide solution used for?
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This organozinc halide is primarily used as a reagent in organic synthesis, particularly in cross-coupling reactions like Negishi couplings, to introduce the 3,5-difluorophenyl group into various organic molecules. It finds applications in the synthesis of pharmaceuticals, advanced materials, and complex organic structures.
What are the CAS number and formula for 3,5-Difluorophenylzinc bromide solution?
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The CAS number is 307531-85-7, and the linear formula is F₂C₆H₃ZnBr.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 3,5-Difluorophenylzinc bromide solution at a concentration of 0.5 M in THF. This product is intended for research and chemical synthesis purposes; TSS does not represent it as USP, BP, EP, or other pharmacopoeia grades.
What are the main hazards associated with this chemical?
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This solution is highly flammable (H225) and can form explosive peroxides. It also causes serious eye irritation (H319) and may cause respiratory irritation (H335). There is a suspicion of cancer (H351). Handling requires strict adherence to safety protocols, including avoiding ignition sources and ensuring adequate ventilation.
How is 3,5-Difluorophenylzinc bromide solution packed, shipped, and exported?
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As a flammable liquid (UN 2056, Hazard Class 3, Packing Group II), it is packaged in compliance with international regulations for hazardous materials transport. Tech Serve Solutions expertly handles global export logistics for this product.
How can I request a sample or a quote for 3,5-Difluorophenylzinc bromide solution?
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Please contact our sales team via the website or direct email to request a quotation or a sample. Specify the required quantity and your delivery location.
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