3,5-Difluoropyridine-2-carboxylic acid
3,5-Difluoropyridine-2-carboxylic acid (CAS: 745784-04-7), with the molecular formula C6H3F2NO2, is a fluorinated heterocyclic building block. This compound is characterised by its pyridine ring substituted with two fluorine atoms and a carboxylic acid group. It serves as a valuable intermediate in organic synthesis, particularly in the development of novel pharmaceuticals and agrochemicals where fluorinated moieties are desired for enhanced biological activity and metabolic stability.
- Synonyms
- C6H3F2NO23,5-Difluoropyridine-2-carboxylic acid

Pharmaceutical Synthesis
3,5-Difluoropyridine-2-carboxylic acid is utilised as a key building block in the synthesis of active pharmaceutical ingredients (APIs). Its fluorinated pyridine structure can impart desirable pharmacokinetic properties to drug candidates.
Agrochemical Development
This compound finds application in the research and development of new agrochemicals, such as herbicides, fungicides, and insecticides. Fluorine substitution can improve the efficacy and environmental profile of crop protection agents.
Materials Science
The unique electronic and structural properties conferred by the difluoropyridine moiety make it a potential intermediate in the design of advanced materials, including functional polymers and organic electronics.
Organic Synthesis Intermediate
As a versatile building block, it is employed in various organic transformations to construct complex molecular architectures relevant to medicinal chemistry and discovery.
| Molecular weight | 159.09 |
|---|---|
| Empirical formula | C6H3F2NO2 |
| Assay | 95% |
| Melting point | 203-208 °C |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Water hazard class (WGK, DE) | 3 |
|---|---|
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3,5-Difluoropyridine-2-carboxylic acid used for?
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3,5-Difluoropyridine-2-carboxylic acid is primarily used as a building block in organic synthesis, especially for the development of pharmaceuticals and agrochemicals. Its fluorinated pyridine structure is valuable for introducing specific properties into target molecules.
What is the CAS number and formula for 3,5-Difluoropyridine-2-carboxylic acid?
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The CAS number is 745784-04-7, and the molecular formula is C6H3F2NO2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 3,5-Difluoropyridine-2-carboxylic acid with a minimum assay of 95%. This product is supplied for research and chemical synthesis purposes and is not intended for pharmaceutical, food, or any other use requiring pharmacopoeia compliance.
How should 3,5-Difluoropyridine-2-carboxylic acid be handled?
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3,5-Difluoropyridine-2-carboxylic acid is classified as a Warning substance, with hazards including skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). Handle with appropriate personal protective equipment, including gloves, eye protection, and respiratory protection, in a well-ventilated area. Avoid breathing dust/fume/gas/mist/vapours/spray. In case of contact with eyes, rinse cautiously with water for several minutes and seek medical advice.
Is 3,5-Difluoropyridine-2-carboxylic acid a controlled substance?
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The provided data does not indicate that 3,5-Difluoropyridine-2-carboxylic acid is a controlled substance.
How is this chemical shipped and exported?
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Tech Serve Solutions is an experienced global supplier and exporter of fine chemicals. This product can be packed and exported according to international shipping regulations for chemical substances.
How can I request a quote or sample?
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To request a quote or a sample of 3,5-Difluoropyridine-2-carboxylic acid, please contact our sales department through the website or by phone.
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