N-Succinyl-Ala-Ala-Pro-Phe p-nitroanilide
N-Succinyl-Ala-Ala-Pro-Phe p-nitroanilide (CAS: 70967-97-4) is a synthetic chromogenic substrate with the molecular formula C30H36N6O9 and a molecular weight of 624.64 g/mol. This compound is primarily utilised in biochemical research for the characterisation and quantification of enzyme activity, particularly those involved in apoptosis and cell signalling pathways. Its specific structure allows for the detection of proteases that cleave the succinyl-alanyl-alanyl-prolyl-phenylalanine sequence.
- IUPAC
- N-Succinyl-Ala-Ala-Pro-Phe-pNA,N-Succinyl-L-alanyl-L-alanyl-L-prolyl-L-phenylalanine 4-nitroanilide
- Synonyms
- N-Succinyl-L-alanyl-L-alanyl-L-prolyl-L-phenylalanine 4-nitroanilide

Enzyme Activity Assays
Utilised as a chromogenic substrate to measure the activity of specific proteases, such as Cathepsin G and Cathepsin L, by detecting the release of p-nitroanilide upon enzymatic cleavage.
Apoptosis Research
Serves as a tool in the study of programmed cell death pathways by enabling the investigation of enzymes implicated in cellular demise.
Biochemical Research
A valuable reagent for understanding cellular signalling cascades and enzymatic mechanisms within biological systems.
| Molecular weight | 624.64 |
|---|---|
| Empirical formula | C30H36N6O9 |
| Storage temperature | −20°C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | human ... FKBP10(60681) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is N-Succinyl-Ala-Ala-Pro-Phe p-nitroanilide used for?
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N-Succinyl-Ala-Ala-Pro-Phe p-nitroanilide (CAS: 70967-97-4) is used as a chromogenic substrate in biochemical research to assay the activity of specific proteases, particularly those involved in apoptosis and cellular signalling.
What are the CAS number and molecular formula?
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The CAS number is 70967-97-4 and the molecular formula is C30H36N6O9.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this compound for research and laboratory use. Specific purity and assay information are available on the product's Certificate of Analysis. It is not supplied as USP, BP, EP, or pharmaceutical grade.
How should this chemical be handled safely?
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Handle with appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. Consult the Safety Data Sheet for detailed handling and hazard information.
Is this product shipped internationally?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, pharmaceutical intermediates, and laboratory reagents.
How can I request a sample or quote?
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Please contact our sales team directly through our website or by phone to request a sample or obtain a quotation for N-Succinyl-Ala-Ala-Pro-Phe p-nitroanilide.
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