3,5-Bis(trifluoromethyl)benzylamine
3,5-Bis(trifluoromethyl)benzylamine (CAS: 85068-29-7) is a valuable organic compound with the linear formula (CF3)2C6H3CH2NH2 and a molecular weight of 243.15 g/mol. It is characterised by the presence of two trifluoromethyl groups, imparting unique electronic properties. This chemical serves as a key building block in complex organic synthesis, particularly in the preparation of specialised phenyl glycine derivatives and other nitrogen-containing compounds for research and development.
- Synonyms
- (CF3)2C6H3CH2NH2

Synthesis of Phenyl Glycine Derivatives
3,5-Bis(trifluoromethyl)benzylamine is utilised as a precursor in the synthesis of specific phenyl glycine derivatives. These derivatives can be of interest in medicinal chemistry and materials science research.
Organic Building Block
As a versatile organic building block, this amine facilitates the introduction of the 3,5-bis(trifluoromethyl)benzyl moiety into various molecular structures. It is employed in custom synthesis projects and for the development of novel chemical entities.
Nitrogen Compound Synthesis
The compound is a useful reagent for creating more complex nitrogen-containing organic molecules. Its distinct trifluoromethyl substituents can influence the properties of the final products.
| Molecular weight | 243.15 |
|---|---|
| Linear formula | (CF3)2C6H3CH2NH2 |
| Assay | 80% |
| Grade | technical grade |
| Application | 3,5-Bis(trifluoromethyl)benzylamine has been used in the preparation of phenyl glycine derivatives1. |
| Melting point | 50-55 °C(lit.) |

Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Flash point | 78 °C / 172.4 °F |
| Transport (UN / ADR) | UN 3259PSN1 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3,5-Bis(trifluoromethyl)benzylamine used for?
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3,5-Bis(trifluoromethyl)benzylamine is primarily used as an organic building block in chemical synthesis, notably for preparing phenyl glycine derivatives and other nitrogen-containing compounds.
What are the CAS number and formula for 3,5-Bis(trifluoromethyl)benzylamine?
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The CAS number is 85068-29-7, and its linear formula is (CF3)2C6H3CH2NH2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 3,5-Bis(trifluoromethyl)benzylamine in technical grade with an assay of 80%. We do not represent this product as USP, BP, or EP grade.
What are the safety considerations for handling 3,5-Bis(trifluoromethyl)benzylamine?
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This compound is classified as Danger, causing severe skin burns and eye damage (H314). Appropriate personal protective equipment, including gloves, eyeshields, and face shields, is essential. Ensure adequate ventilation and use a suitable respirator.
How is 3,5-Bis(trifluoromethyl)benzylamine shipped?
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Tech Serve Solutions exports and supplies 3,5-Bis(trifluoromethyl)benzylamine globally. Specific packaging and shipping details are available upon request, adhering to all relevant transport regulations (UN 3259 PSN1 8 / PGII).
How can I request a quote or sample?
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To request a quote or sample of 3,5-Bis(trifluoromethyl)benzylamine, please contact our sales team through the website or by phone. Provide your specific requirements for prompt assistance.
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