3,5-Bis(trifluoromethyl)benzyl bromide
3,5-Bis(trifluoromethyl)benzyl bromide (CAS: 32247-96-4), a halogenated hydrocarbon with the linear formula (CF3)2C6H3CH2Br and a molecular weight of 307.03 g/mol, serves as a valuable building block in organic synthesis. This aryl compound, with an assay of 97%, is primarily utilised for its reactivity in chemical synthesis, facilitating the introduction of the 3,5-bis(trifluoromethyl)benzyl moiety into various molecular structures. Its applications span pharmaceutical research and the development of complex organic molecules.
- IUPAC
- 1-(Bromomethyl)-3,5-bis(trifluoromethyl)benzene
- Synonyms
- (CF3)2C6H3CH2Br1-(Bromomethyl)-3,5-bis(trifluoromethyl)benzene
Derivatisation Reagent
Used as a derivatisation reagent in the detection of uracil in DNA. This application employs GC and negative chemical ionisation mass spectrometry for analysis.
Enantioselective Synthesis
Applied in the enantioselective synthesis of non-peptidic neurokinin NK1 receptor antagonists. An example includes its role in the synthesis of L-733,060.
Organic Building Block
Functions as a key building block in organic synthesis, particularly for introducing the 3,5-bis(trifluoromethyl)benzyl group into target molecules for further functionalisation.
| Molecular weight | 307.03 |
|---|---|
| Linear formula | (CF3)2C6H3CH2Br |
| Assay | 97% |
| Density | 1.675 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.445(lit.) |
| Application | 3,5-Bis(trifluoromethyl)benzyl bromide has been used:• as derivatization reagent in detection of uracil in DNA by GC and negative chemical ionization mass spectrometry1• in enantioselective synthesis of non-peptidic neurokinin NK1 receptor antagonist, L-733,0602 |
Hazard statements
- H226Flammable liquid and vapour
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 26 °C / 78.8 °F |
| Transport (UN / ADR) | UN 2920 3(8) / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 10-34 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3,5-Bis(trifluoromethyl)benzyl bromide used for?
+
3,5-Bis(trifluoromethyl)benzyl bromide is used as a derivatisation reagent for DNA analysis and in the enantioselective synthesis of pharmaceutical intermediates, serving as a versatile building block in organic chemistry.
What is the CAS number and formula for 3,5-Bis(trifluoromethyl)benzyl bromide?
+
The CAS number for 3,5-Bis(trifluoromethyl)benzyl bromide is 32247-96-4, and its linear formula is (CF3)2C6H3CH2Br.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies 3,5-Bis(trifluoromethyl)benzyl bromide with a minimum assay of 97%. It is supplied for research and chemical synthesis purposes and is not represented as USP, BP, or EP grade.
How should 3,5-Bis(trifluoromethyl)benzyl bromide be handled safely?
+
3,5-Bis(trifluoromethyl)benzyl bromide is a Danger hazard. It is flammable (H226) and causes severe skin burns and eye damage (H314). Appropriate personal protective equipment, including gloves, eye protection, and respiratory protection, must be used. Handle in a well-ventilated area, away from ignition sources.
Is 3,5-Bis(trifluoromethyl)benzyl bromide packed and exported by TSS?
+
Yes, Tech Serve Solutions, as a specialist global supplier and exporter of fine chemicals, packages and exports 3,5-Bis(trifluoromethyl)benzyl bromide. It is shipped according to UN 2920 regulations.
How can I request a sample or quote for 3,5-Bis(trifluoromethyl)benzyl bromide?
+
To request a sample or a quote for 3,5-Bis(trifluoromethyl)benzyl bromide, please contact our sales department through the website or by calling us directly. We aim to respond promptly to all inquiries.
▶ Related products
1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis
1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis