3,5-Bis(trifluoromethyl)benzyl chloride
3,5-Bis(trifluoromethyl)benzyl chloride (CAS 75462-59-8) is a halogenated hydrocarbon and an organic building block, identified by the linear formula (CF3)2C6H3CH2Cl and a molecular weight of 262.58 g/mol. This compound serves as a key intermediate in chemical synthesis, particularly in the preparation of other complex organic molecules. Its specific structure, featuring two trifluoromethyl groups on the benzyl chloride core, makes it valuable for introducing these electron-withdrawing functionalities into target compounds.
- IUPAC
- 1-(Chloromethyl)-3,5-bis(trifluoromethyl)benzene
- Synonyms
- (CF3)2C6H3CH2Cl1-(Chloromethyl)-3,5-bis(trifluoromethyl)benzene

Synthesis of Azido Compounds
3,5-Bis(trifluoromethyl)benzyl chloride is utilised as a precursor in organic synthesis. It has been employed in the preparation of 1-(azidomethyl)-3,5-bis(trifluoromethyl)benzene, highlighting its utility in functional group transformations.
Building Block for Specialty Chemicals
As an aryl building block, this compound is instrumental in constructing more complex molecules. The presence of trifluoromethyl groups allows for the introduction of specific electronic and steric properties into novel chemical entities.
Intermediate in Halogenated Hydrocarbon Chemistry
This chemical falls under the category of halogenated hydrocarbons. Its reactive benzyl chloride moiety facilitates various substitution reactions, making it a versatile intermediate for further chemical modifications.
| Molecular weight | 262.58 |
|---|---|
| Linear formula | (CF3)2C6H3CH2Cl |
| Assay | 98% |
| Application | 3,5-Bis(trifluoromethyl)benzyl chloride has been used in the preparation of 1-(azidomethyl)-3,5-bis-(trifluoromethyl)benzene1. |
| Melting point | 29-32 °C(lit.) |

Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Flash point | 71 °C / 159.8 °F |
| Transport (UN / ADR) | UN 3261 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3,5-Bis(trifluoromethyl)benzyl chloride used for?
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3,5-Bis(trifluoromethyl)benzyl chloride is primarily used as a building block in chemical synthesis for creating more complex organic molecules, such as 1-(azidomethyl)-3,5-bis(trifluoromethyl)benzene.
What is the CAS number and chemical formula for 3,5-Bis(trifluoromethyl)benzyl chloride?
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The CAS number is 75462-59-8, and its linear formula is (CF3)2C6H3CH2Cl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 3,5-Bis(trifluoromethyl)benzyl chloride with an assay of 98%. This product is not represented as USP, BP, EP, or any other pharmacopoeia grade.
How should 3,5-Bis(trifluoromethyl)benzyl chloride be handled safely?
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This compound is classified as Danger, causing severe skin burns and eye damage (H314). Appropriate personal protective equipment, including eyeshields, face shields, and chemical-resistant gloves, is essential. Ensure adequate ventilation and consult the Safety Data Sheet for detailed handling procedures.
Can Tech Serve Solutions export 3,5-Bis(trifluoromethyl)benzyl chloride?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including 3,5-Bis(trifluoromethyl)benzyl chloride.
How can I request a quote or sample?
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To request a quote or a sample of 3,5-Bis(trifluoromethyl)benzyl chloride, please contact the Tech Serve Solutions sales team through our website or by telephone.
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