(2R,5R)-(−)-trans-2,5-Dimethylpyrrolidine
(2R,5R)-(−)-trans-2,5-Dimethylpyrrolidine (CAS: 62617-70-3) is a chiral heterocyclic compound with the molecular formula C6H13N and a molecular weight of 99.17 g/mol. This enantiomerically pure pyrrolidine derivative is primarily utilised as a chiral building block in asymmetric synthesis. Its specific stereochemistry makes it valuable for constructing complex molecules where precise spatial arrangement is critical, particularly in pharmaceutical research and development.
- Synonyms
- 62617-70-3
Asymmetric Synthesis
Utilised as a chiral auxiliary or building block in stereoselective reactions. It enables the synthesis of enantiomerically enriched compounds, crucial for pharmaceuticals and fine chemicals.
Chiral Ligand Development
Serves as a precursor for chiral ligands used in transition metal catalysis. These ligands can induce high enantioselectivity in various catalytic transformations.
Pharmaceutical Intermediates
A key intermediate in the synthesis of complex active pharmaceutical ingredients (APIs). Its defined stereochemistry is essential for biological activity.
Research and Development
Employed in academic and industrial research settings to explore novel synthetic methodologies and develop new chiral molecules with potential applications.
| Molecular weight | 99.17 |
|---|---|
| Empirical formula | C6H13N |
| Assay | ≥97.0% (GC) |
| Density | 0.852 g/mL at 20 °C(lit.) |
| Refractive index | n20/D 1.431 |
| Optical activity | [α]20/D −19.0±1.5°, c = 2% in methylene chloride |
| Storage temperature | 2-8°C |
Hazard statements
- H225Highly flammable liquid and vapour
- H302Harmful if swallowed
- H314Causes severe skin burns and eye damage
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 7 °C / 44.6 °F |
| Transport (UN / ADR) | UN 2924 3/PG 2 |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,C |
| Risk statements (R) | 11-22-34 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (2R,5R)-(−)-trans-2,5-Dimethylpyrrolidine used for?
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This compound is primarily used as a chiral building block in asymmetric synthesis and for the development of chiral ligands for catalysis, particularly in pharmaceutical research.
What are the CAS number and formula for (2R,5R)-(−)-trans-2,5-Dimethylpyrrolidine?
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The CAS number is 62617-70-3 and the empirical formula is C6H13N.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (2R,5R)-(−)-trans-2,5-Dimethylpyrrolidine with an assay of ≥97.0% (GC). TSS does not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should (2R,5R)-(−)-trans-2,5-Dimethylpyrrolidine be handled safely?
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(2R,5R)-(−)-trans-2,5-Dimethylpyrrolidine is a flammable liquid and vapour, harmful if swallowed, and causes severe skin burns and eye damage. Handle with appropriate personal protective equipment, including gloves, eye protection, and respiratory protection, in a well-ventilated area away from ignition sources.
Is (2R,5R)-(−)-trans-2,5-Dimethylpyrrolidine shipped internationally?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals and laboratory reagents, including (2R,5R)-(−)-trans-2,5-Dimethylpyrrolidine.
How can I request a sample or quote for (2R,5R)-(−)-trans-2,5-Dimethylpyrrolidine?
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Please contact our sales team via our website or direct email to request a sample or a quotation for (2R,5R)-(−)-trans-2,5-Dimethylpyrrolidine.
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