(2R,5S)-2-Trichloromethyl-3-oxa-1-azabicyclo[3.3.0]octan-4-one
(2R,5S)-2-Trichloromethyl-3-oxa-1-azabicyclo[3.3.0]octan-4-one (CAS 97538-67-5) is a chiral heterocyclic compound with a molecular weight of 244.50 g/mol. This compound serves as a valuable precursor in asymmetric synthesis. Its specific stereochemistry makes it useful for creating enantiomerically pure amino acid derivatives, particularly in the synthesis of protected proline analogues. TSS offers this chemical for research and development purposes.
- IUPAC
- (3R-cis)-Tetrahydro-3-(trichloromethyl)-1H,3H-pyrrolo[1,2-c]oxazol-1-one,L-Proline - chloral condensation product
- Synonyms
- C7H8Cl3NO2(3R-cis)-Tetrahydro-3-(trichloromethyl)-1H,3H-pyrrolo[1,2-c]oxazol-1-one
![(2R,5S)-2-Trichloromethyl-3-oxa-1-azabicyclo[3.3.0]octan-4-one (C7H8Cl3NO2) — chemical structure, CAS 97538-67-5; Chemistry, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F97538-67-5.png&w=3840&q=75)
Precursor for Enantiopure Proline Derivatives
This compound is a key intermediate for the synthesis of enantiomerically pure C- and N-protected α-alkyl prolines. Its defined stereochemistry is crucial for building chiral centres in complex molecules.
Chiral Building Block in Organic Synthesis
As a chiral heterocyclic building block, it facilitates the introduction of specific stereochemical features into target molecules. This is particularly relevant in the development of pharmaceuticals and fine chemicals.
Asymmetric Synthesis
Its unique structure and stereochemical properties make it suitable for use in asymmetric synthesis methodologies, enabling the creation of chiral compounds with high enantiomeric purity.
| Molecular weight | 244.50 |
|---|---|
| Empirical formula | C7H8Cl3NO2 |
| Assay | ≥98.0% (AT) |
| Optical activity | [α]/D 29 to 34°, c = 2 in toluene |
| Application | Valuable precursor to enantiomerically pure C- and N-protected α-alkyl prolines1. |
| Melting point | 108-112 °C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (2R,5S)-2-Trichloromethyl-3-oxa-1-azabicyclo[3.3.0]octan-4-one used for?
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(2R,5S)-2-Trichloromethyl-3-oxa-1-azabicyclo[3.3.0]octan-4-one is used as a valuable precursor for the synthesis of enantiomerically pure C- and N-protected α-alkyl prolines and as a chiral building block in asymmetric synthesis.
What are the CAS number and formula for this chemical?
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The CAS number is 97538-67-5 and the empirical formula is C7H8Cl3NO2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this chemical with an assay of ≥98.0% (AT). TSS does not represent this product as USP, BP, or EP grade.
How should (2R,5S)-2-Trichloromethyl-3-oxa-1-azabicyclo[3.3.0]octan-4-one be handled?
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Handling requires appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. This compound has a WGK rating of 3 in Germany.
How is this chemical packed, shipped, and exported?
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Tech Serve Solutions, a specialist global supplier and exporter, ensures appropriate packaging and shipping for chemicals like this, adhering to international regulations for export.
How can I request a sample or quote for (2R,5S)-2-Trichloromethyl-3-oxa-1-azabicyclo[3.3.0]octan-4-one?
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To request a sample or a quote, please contact our sales team through the website or by phone, providing the product name and CAS number (97538-67-5).
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