(2R,5R)-1-(2-(1,3-Dioxolan-2-yl)phenyl)-2,5-dimethylphospholane
(2R,5R)-1-(2-(1,3-Dioxolan-2-yl)phenyl)-2,5-dimethylphospholane (CAS 1044256-04-3) is a chiral phospholane ligand with a molecular weight of 264.30 g/mol. This compound is a valuable tool in asymmetric synthesis, frequently employed as a chiral catalyst or ligand. Its specific stereochemistry enables high enantioselectivity in various chemical transformations, making it crucial for the synthesis of complex chiral molecules in the pharmaceutical and fine chemical industries.
- IUPAC
- R,R-Me-RajPhos™
- Synonyms
- 5-dimethylphospholane,1044256-04-3, C15H21O2P
Asymmetric Catalysis
This phospholane serves as a privileged chiral ligand in transition metal-catalyzed asymmetric reactions, facilitating the synthesis of enantiomerically enriched compounds.
Chiral Synthesis
It is instrumental in constructing chiral centres with high stereocontrol, essential for the development of pharmaceuticals and other complex organic molecules.
Ligand for Metal Complexes
As a phospholane-based ligand, it forms stable complexes with various metals, which are then used as catalysts in a range of synthetic applications.
| Molecular weight | 264.30 |
|---|---|
| Empirical formula | C15H21O2P |
| Density | 1.1052 g/mL at 25 °C |
| Refractive index | n20/D 1.572 |
| Optical activity | [α]22/D -38.0°, c = 1 in chloroform |
| Application | Kanata purity |
| Flash point | >110 °C / >230 °F |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (2R,5R)-1-(2-(1,3-Dioxolan-2-yl)phenyl)-2,5-dimethylphospholane primarily used for?
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This compound is primarily used as a chiral ligand in asymmetric catalysis and for the synthesis of chiral molecules.
What are the CAS number and molecular formula?
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The CAS number is 1044256-04-3, and the molecular formula is C15H21O2P.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this chemical at a purity indicated by its refractive index (n20/D 1.572) and density (1.1052 g/mL at 25 °C). It is supplied for research and technical applications. TSS does not represent this product as USP, BP, EP, or other pharmacopoeia grades unless explicitly stated in the product specifications.
How should (2R,5R)-1-(2-(1,3-Dioxolan-2-yl)phenyl)-2,5-dimethylphospholane be handled?
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This compound has a flash point greater than 110 °C (230 °F) and a WGK Germany rating of 3, indicating it is hazardous. Handle with appropriate personal protective equipment in a well-ventilated area, away from ignition sources.
Is this chemical available for export?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, pharmaceutical intermediates, and laboratory reagents, including this product.
How can I request a sample or quote?
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Please contact our sales team via the website or by telephone to request a sample or a quotation for (2R,5R)-1-(2-(1,3-Dioxolan-2-yl)phenyl)-2,5-dimethylphospholane.
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