(2R,4S,5R)-2-Hydroxymethyl-5-ethylquinuclidine
(2R,4S,5R)-2-Hydroxymethyl-5-ethylquinuclidine (CAS: 219794-81-7), a chiral amine with the molecular formula C10H19NO, is a key building block in asymmetric synthesis. Its unique stereochemistry makes it valuable for developing enantioselective catalysts and ligands, facilitating the production of specific stereoisomers in complex chemical reactions. TSS supplies this high-purity compound for advanced research and development in chemical synthesis.
- IUPAC
- (2R,4S,5R)-5-Ethyl-2-quinuclidinylmethanol
- Synonyms
- 219794-81-7(2R,4S,5R)-5-Ethyl-2-quinuclidinylmethanol
Asymmetric Synthesis
Utilised as a chiral auxiliary or precursor in asymmetric synthesis, enabling the stereoselective construction of complex organic molecules. Its defined stereocentres are crucial for achieving high enantiomeric excess in synthetic transformations.
Catalyst and Ligand Development
Serves as a foundational component for the design and synthesis of novel chiral catalysts and ligands. These sophisticated systems are employed to control stereochemical outcomes in a variety of catalysed reactions, including asymmetric hydrogenations and alkylations.
Pharmaceutical Intermediate
Acts as a valuable intermediate in the multi-step synthesis of pharmaceutically active compounds. Its chiral nature is often exploited to introduce or control specific stereocentres within drug candidates.
| Molecular weight | 169.26 |
|---|---|
| Empirical formula | C10H19NO |
| Assay | ≥98.0% (GC) |
| Optical activity | [α]/D +178±5°, c = 1 in chloroform |
| Storage temperature | 2-8°C |
Hazard statements
- H315Causes skin irritation
- H318Causes serious eye damage
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 2 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 37/38-41 |
| Safety statements (S) | 26-39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (2R,4S,5R)-2-Hydroxymethyl-5-ethylquinuclidine used for?
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(2R,4S,5R)-2-Hydroxymethyl-5-ethylquinuclidine is primarily used in asymmetric synthesis as a building block for chiral catalysts, ligands, and as an intermediate in the synthesis of complex organic molecules, particularly within pharmaceutical research.
What is the CAS number and formula for (2R,4S,5R)-2-Hydroxymethyl-5-ethylquinuclidine?
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The CAS number for (2R,4S,5R)-2-Hydroxymethyl-5-ethylquinuclidine is 219794-81-7, and its empirical formula is C10H19NO.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (2R,4S,5R)-2-Hydroxymethyl-5-ethylquinuclidine with a purity of ≥98.0% (GC). TSS does not represent this product as USP, BP, EP or other pharmacopoeia grades unless explicitly stated.
How should (2R,4S,5R)-2-Hydroxymethyl-5-ethylquinuclidine be handled safely?
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Handling requires appropriate personal protective equipment including eyeshields and gloves. Due to its irritant properties (H315, H335) and risk of serious eye damage (H318), ensure adequate ventilation and avoid contact with skin, eyes, and respiratory tract. Refer to the Safety Data Sheet for detailed guidance.
Is this chemical controlled or scheduled?
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The provided data does not indicate that (2R,4S,5R)-2-Hydroxymethyl-5-ethylquinuclidine is a controlled or scheduled substance.
How is this product shipped and exported?
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Tech Serve Solutions is a global supplier and exporter of chemicals, adhering to all necessary regulations for the safe and compliant shipment of laboratory reagents and fine chemicals worldwide.
How can I request a quote or sample?
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Please contact our sales team through the website or by phone to request a quotation or a sample of (2R,4S,5R)-2-Hydroxymethyl-5-ethylquinuclidine.
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