(2R,4S,5R)-2-Aminomethyl-5-ethylquinuclidine
(2R,4S,5R)-2-Aminomethyl-5-ethylquinuclidine (CAS: 475160-61-3) is a chiral quinuclidine derivative with the empirical formula C10H20N2 and a molecular weight of 168.28 g/mol. This compound is valuable in asymmetric synthesis and as a chiral building block. It serves as a key intermediate in the development of novel pharmaceuticals and complex organic molecules, leveraging its specific stereochemistry for targeted chemical transformations. It is supplied by Tech Serve Solutions for research and development purposes.
- IUPAC
- (2R,4S,5R)-5-Ethyl-2-quinuclidinylmethylamine
- Synonyms
- 475160-61-3C10H20N2(2R,4S,5R)-5-Ethyl-2-quinuclidinylmethylamine

Chiral Building Block
Utilised in the synthesis of complex chiral molecules where precise stereochemical control is essential. Its rigid quinuclidine framework provides a well-defined scaffold for asymmetric transformations.
Asymmetric Synthesis Reagent
Employable as a chiral auxiliary or ligand in enantioselective reactions. Its structure is amenable to the development of catalytic systems for producing optically pure compounds.
Pharmaceutical Intermediate
Serves as a crucial intermediate in the multi-step synthesis of active pharmaceutical ingredients (APIs). Its specific stereochemistry can be leveraged to construct targeted drug candidates.
Ligand Development
Can be incorporated into the design of novel ligands for organometallic catalysis. The quinuclidine motif offers unique coordination properties.
| Molecular weight | 168.28 |
|---|---|
| Empirical formula | C10H20N2 |
| Assay | ≥95.0% (GC) |
| Storage temperature | 2-8°C |


Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H318Causes serious eye damage
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 2 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-37/38-41 |
| Safety statements (S) | 26-39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (2R,4S,5R)-2-Aminomethyl-5-ethylquinuclidine used for?
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(2R,4S,5R)-2-Aminomethyl-5-ethylquinuclidine is primarily used as a chiral building block and reagent in asymmetric synthesis. It finds applications as an intermediate in the development of pharmaceuticals and other complex chiral molecules.
What is the CAS number and formula for (2R,4S,5R)-2-Aminomethyl-5-ethylquinuclidine?
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The CAS number is 475160-61-3 and the empirical formula is C10H20N2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (2R,4S,5R)-2-Aminomethyl-5-ethylquinuclidine with an assay of ≥95.0% (GC). This is a research or technical grade chemical and is not represented as USP, BP, EP, or any pharmacopoeial standard.
How should (2R,4S,5R)-2-Aminomethyl-5-ethylquinuclidine be handled safely?
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This compound is classified as Danger. It is harmful if swallowed (H302), causes skin irritation (H315), causes serious eye damage (H318), and may cause respiratory irritation (H335). Always use appropriate personal protective equipment, including eyeshields, gloves, and a dust mask (type N95 or equivalent). Ensure adequate ventilation and avoid breathing dust. In case of eye contact, rinse cautiously with water for several minutes, removing contact lenses if present and easy to do. Continue rinsing.
Is this chemical a controlled substance?
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The provided data does not indicate that (2R,4S,5R)-2-Aminomethyl-5-ethylquinuclidine is a controlled substance.
How is this product packed and shipped?
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Tech Serve Solutions expertly packs and exports fine chemicals globally. Specific packaging details depend on the quantity ordered and transportation regulations. Please contact us for detailed shipping information.
How can I request a sample or quote?
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To request a sample or a quote for (2R,4S,5R)-2-Aminomethyl-5-ethylquinuclidine, please contact our sales team via the website or direct inquiry channels, providing your specific requirements.
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