2-(Trifluoromethyl)-D-phenylalanine
2-(Trifluoromethyl)-D-phenylalanine (CAS: 130930-49-3; Formula: C10H10F3NO2) is a non-proteinogenic amino acid derivative featuring a trifluoromethyl group attached to the phenyl ring. This structural modification imparts unique electronic and lipophilic properties, making it a valuable building block. It is primarily utilised in chemical synthesis and peptide chemistry, particularly for the introduction of unnatural amino acid residues into peptide chains to modulate their properties and functions.
- IUPAC
- (R)-2-Amino-3-[2-(trifluoromethyl)phenyl]propionic acid
Peptide Synthesis
Incorporation into peptides to create unnatural analogues. This can enhance metabolic stability, alter receptor binding affinity, or introduce conformational constraints.
Chemical Synthesis
Serves as a chiral building block for the synthesis of complex organic molecules. Its trifluoromethyl moiety can influence reactivity and molecular properties.
Chemical Biology
Used as a probe or tool compound in biological research to investigate protein function or enzyme mechanisms. The trifluoromethyl group can be useful for spectroscopic studies.
| Molecular weight | 233.19 |
|---|---|
| Empirical formula | C10H10F3NO2 |
| Assay | ≥98.0% |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-(Trifluoromethyl)-D-phenylalanine used for?
+
2-(Trifluoromethyl)-D-phenylalanine is used in chemical synthesis, peptide chemistry, and chemical biology as a building block for creating modified peptides and complex organic molecules. It allows for the introduction of unnatural amino acid residues.
What are the CAS number and formula for 2-(Trifluoromethyl)-D-phenylalanine?
+
The CAS number is 130930-49-3, and the empirical formula is C10H10F3NO2.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies 2-(Trifluoromethyl)-D-phenylalanine with an assay of ≥98.0%. This product is intended for research and chemical synthesis purposes and is not supplied as USP, BP, EP, or pharmaceutical grade.
What are the safety considerations when handling 2-(Trifluoromethyl)-D-phenylalanine?
+
Handling requires appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. The substance has a WGK Germany rating of 3, indicating a high hazard to water.
How is 2-(Trifluoromethyl)-D-phenylalanine packed and shipped?
+
Tech Serve Solutions, as a specialist global supplier and exporter, ensures appropriate packaging and shipping protocols are followed for this chemical, adhering to international regulations.
How can I request a quote or sample for 2-(Trifluoromethyl)-D-phenylalanine?
+
To request a quote or a sample of 2-(Trifluoromethyl)-D-phenylalanine, please contact our sales team through the website or direct enquiry form.
▶ Related products
1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis
1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis