2-(Trifluoromethyl)-DL-phenylglycine
2-(Trifluoromethyl)-DL-phenylglycine (CAS 240490-00-0) is a chiral amino acid derivative with the molecular formula C9H8F3NO2 and a molecular weight of 219.16 g/mol. This compound is valuable in chemical synthesis and peptide chemistry. It serves as a building block for creating complex molecules, particularly in the field of chemical biology and for the development of unnatural amino acid analogues.
- IUPAC
- (±)-2-Amino-2-[2-(trifluoromethyl)phenyl]acetic acid

Chemical Synthesis Intermediate
Utilised as a key intermediate in the synthesis of more complex organic molecules. Its trifluoromethyl group offers unique electronic and steric properties for drug discovery and material science.
Peptide Chemistry
Incorporated into peptide chains to introduce modified amino acid residues. This allows for the study of peptide structure-activity relationships and the development of novel peptidomimetics.
Chemical Biology Research
Employed in research settings to probe biological pathways and develop new biochemical tools. Its unnatural structure can confer unique properties to biologically active molecules.
Unnatural Amino Acid Analogues
Serves as a precursor for the synthesis of various unnatural amino acid derivatives, expanding the scope of available building blocks for medicinal chemistry.
| Molecular weight | 219.16 |
|---|---|
| Empirical formula | C9H8F3NO2 |
| Assay | ≥98.0% |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-(Trifluoromethyl)-DL-phenylglycine used for?
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2-(Trifluoromethyl)-DL-phenylglycine is primarily used as an intermediate in chemical synthesis, peptide chemistry, chemical biology research, and for creating unnatural amino acid analogues.
What are the CAS number and formula for 2-(Trifluoromethyl)-DL-phenylglycine?
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The CAS number for 2-(Trifluoromethyl)-DL-phenylglycine is 240490-00-0, and its empirical formula is C9H8F3NO2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-(Trifluoromethyl)-DL-phenylglycine with an assay of ≥98.0%. We do not represent this product as USP, BP, EP, or other pharmacopoeia grades.
What are the primary safety concerns when handling this chemical?
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This compound is a Warning substance that causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Appropriate personal protective equipment, including eyeshields, gloves, and a dust mask (type N95 or equivalent), should be used.
How is 2-(Trifluoromethyl)-DL-phenylglycine packed and shipped?
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As a global supplier and exporter, Tech Serve Solutions ensures that 2-(Trifluoromethyl)-DL-phenylglycine is carefully packed and shipped in compliance with all relevant regulations for chemical transport.
How can I request a sample or obtain a quote for 2-(Trifluoromethyl)-DL-phenylglycine?
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To request a sample or a quote, please use the 'Contact Us' form on our website or reach out to our sales department directly with your inquiry.
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