D-Fructose 1,6-bisphosphate trisodium salt hydrate
D-Fructose 1,6-bisphosphate trisodium salt hydrate is a vital biochemical intermediate, identified by CAS number 38099-82-0 (anhydrous basis). With a molecular weight of 406.06 (anhydrous basis) and the empirical formula C6H11Na3O12P2 · xH2O, it plays a crucial role in the glycolytic pathway. This compound serves as a precursor to key metabolic intermediates and is recognized for its function as an allosteric activator of enzymes, making it valuable in biochemical research and metabolic studies.
- IUPAC
- D(+)Fructofuranose 1,6-diphosphate trisodium salt hydrate,Harden-Young ester,Hexose diphosphate trisodium salt hydrate
- Synonyms
- D-Fructose-1,6-bisphosphate trisodium salt hydrateD(+)Fructofuranose 1,6-diphosphate trisodium salt hydrateHarden-Young esterHexose diphosphate trisodium salt hydrate

Biochemical Research
Utilised as a substrate for enzyme identification and characterization, particularly for fructose-1,6-bisphosphate aldolase(s) and fructose-1,6-bisphosphatase(s). It also functions as an allosteric activator or inhibitor for various enzymes within metabolic pathways.
Glycolysis Pathway Studies
Serves as a direct precursor to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate in the glycolytic pathway. This makes it an essential compound for studying cellular energy metabolism and related biochemical processes.
Neuroprotection Research
Investigated for its potential neuroprotective properties, particularly in the context of brain injury. This highlights its emerging role in biomedical research beyond basic metabolism.
| Molecular weight | 406.06 (anhydrous basis) |
|---|---|
| Empirical formula | C6H11Na3O12P2 · xH2O |
| Assay | ≥98% (TLC) |
| Storage temperature | −20°C |
| Application | D-Fructose-1,6-bisphosphate (FBP), a common metabolic sugar, is the precursor of glyceraldehyde 3-phosphate and dihydroxyacetone phosphate in the glycolytic pathway.1 It may be used as an allosteric activator of enzymes such as pyruvate kinase and NAD+-dependent L-(+)-lactate dehydrogenase, as an inhibitor of acetate kinase and as a substrate to identify and characterize enzymes such as fructose-1,6-bisphosphate aldolase(s) and fructose-1,6-bisphosphatase(s). FBP is studied as a neuroprotective agent in brain injury.2 |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is D-Fructose 1,6-bisphosphate trisodium salt hydrate used for?
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It is used as a precursor in the glycolytic pathway, an allosteric activator/inhibitor of enzymes, a substrate for enzyme characterization, and is studied for neuroprotective effects in brain injury.
What is the CAS number and chemical formula for D-Fructose 1,6-bisphosphate trisodium salt hydrate?
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The CAS number for the anhydrous form is 38099-82-0, and the empirical formula is C6H11Na3O12P2 · xH2O.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies D-Fructose 1,6-bisphosphate trisodium salt hydrate with an assay of ≥98% (TLC). This product is intended for research and laboratory use and is not represented as USP, BP, EP, or pharmacopoeia grade.
How should D-Fructose 1,6-bisphosphate trisodium salt hydrate be handled and stored?
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Handle with appropriate personal protective equipment, including eyeshields, gloves, and a type N95 (US) or type P1 (EN143) respirator filter. Store at -20°C. This compound has a WGK Germany rating of 3, indicating it is hazardous to water.
How is D-Fructose 1,6-bisphosphate trisodium salt hydrate packed, shipped, and exported?
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Tech Serve Solutions packs, ships, and exports fine chemicals globally, adhering to all necessary regulations for safe and compliant transport of laboratory reagents.
How can I request a sample or quote for D-Fructose 1,6-bisphosphate trisodium salt hydrate?
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Please contact our sales team directly via phone or email to request a sample or obtain a quotation for D-Fructose 1,6-bisphosphate trisodium salt hydrate.
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