2-(Trifluoromethyl)aniline
2-(Trifluoromethyl)aniline (CAS: 88-17-5), with the molecular formula CF3C6H4NH2 and a molecular weight of 161.12 g/mol, is an aromatic amine featuring a trifluoromethyl group. This compound is recognised for its utility as a building block and intermediate in organic synthesis. Its properties make it valuable in the development of pharmaceuticals, agrochemicals, and various specialty chemicals, serving as a key component in complex molecular constructions.
- IUPAC
- α,α,α-Trifluoro-o-toluidine,2-Aminobenzotrifluoride
- Synonyms
- 2-Aminobenzotrifluorideα,α,α-Trifluoro-o-toluidine
Pharmaceutical Intermediates
Utilised as a crucial building block in the synthesis of active pharmaceutical ingredients (APIs). Its trifluoromethyl group can impart desirable pharmacokinetic properties to drug candidates.
Agrochemical Synthesis
Serves as an intermediate in the production of pesticides, herbicides, and fungicides. The trifluoromethylaniline moiety is common in many agrochemical structures.
Dye and Pigment Manufacturing
Employed in the synthesis of specialised dyes and pigments, where the fluorinated aromatic structure can influence colour and stability properties.
Organic Synthesis Reagent
A versatile reagent for introducing the 2-(trifluoromethyl)phenyl group into organic molecules. It is essential for constructing complex molecular frameworks in research and development.
| Molecular weight | 161.12 |
|---|---|
| Linear formula | CF3C6H4NH2 |
| Assay | 99% |
| Boiling point | 170-173 °C(lit.)68 °C/15 mmHg(lit.) |
| Density | 1.282 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.481(lit.) |
| Melting point | 34 °C(lit.) |
Hazard statements
- H226Flammable liquid and vapour
- H301Toxic if swallowed
- H311Toxic in contact with skin
- H331Toxic if inhaled
- H373May cause damage to organs through prolonged exposure
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P301IF SWALLOWED
- P311Call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 55 °C / 131 °F |
| Transport (UN / ADR) | UN 2942 6.1 / PGIII |
| Water hazard class (WGK, DE) | 1 |
| Hazard codes (EU) | T |
| Risk statements (R) | 10-23/24/25-33 |
| Safety statements (S) | 36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-(Trifluoromethyl)aniline used for?
+
2-(Trifluoromethyl)aniline is primarily used as a building block and intermediate in the synthesis of pharmaceuticals, agrochemicals, dyes, and other complex organic compounds.
What is the CAS number and molecular formula?
+
The CAS number for 2-(Trifluoromethyl)aniline is 88-17-5, and its molecular formula is CF3C6H4NH2.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies 2-(Trifluoromethyl)aniline with an assay of 99%. TSS does not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should 2-(Trifluoromethyl)aniline be handled safely?
+
2-(Trifluoromethyl)aniline is a Danger substance (GHS02, GHS06, GHS08) that is flammable (H226) and toxic if swallowed, in contact with skin, or if inhaled (H301, H311, H331). It may also cause damage to organs through prolonged exposure (H373). Handling requires stringent safety measures, including appropriate personal protective equipment such as eyeshields, gloves, and a suitable respirator, and should only be performed in well-ventilated areas.
How is this chemical packed and exported?
+
2-(Trifluoromethyl)aniline is shipped under UN 2942 classification, hazard class 6.1, packing group III. TSS handles all aspects of packing and export in compliance with international regulations.
How can I request a quote or sample?
+
To request a quote or a sample of 2-(Trifluoromethyl)aniline, please contact our sales team through the website or by phone.
▶ Related products
1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis
1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis