(R)-α-Methoxy-2-naphthylacetic acid

CAS 156942-67-5C13H12O3Chemical Synthesis

(R)-α-Methoxy-2-naphthylacetic acid (CAS: 156942-67-5, C13H12O3) is a chiral carboxylic acid with a molecular weight of 216.23. This enantiomerically pure compound serves as a valuable building block in asymmetric synthesis, facilitating the creation of complex chiral molecules. Its specific optical activity and high enantiomeric purity make it a sought-after reagent for researchers in organic chemistry and pharmaceutical development.

IUPAC: (R)-α-Methoxy-2-naphthaleneacetic acid,(R)-2-NMA

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(R)-α-Methoxy-2-naphthylacetic acid (C13H12O3) — chemical structure, CAS 156942-67-5; Chemistry, fine chemical supplied by Tech Serve Solutions

Asymmetric SynthesisCarboxylic AcidsChemical SynthesisChiral Building BlocksOrganic Building Blocks

01 /Applications

Chiral Building Block

Utilised as a key intermediate in the synthesis of enantiomerically pure compounds. Its defined stereochemistry allows for precise control in the construction of complex chiral targets.

Asymmetric Synthesis

Essential reagent for stereoselective reactions, enabling chemists to produce specific enantiomers of pharmaceutical intermediates and fine chemicals with high optical purity.

Organic Synthesis

A versatile carboxylic acid derivative employed in various organic transformations requiring a naphthalene scaffold and specific chiral induction.

02 /Properties

Molecular weight	216.23
Empirical formula	C13H12O3
Assay	≥99.0% (HPLC)≥99.0%
Optical activity	[α]/D -177±5°, c = 0.1 in methanol
Optical purity	enantiomeric excess: ≥99.0% (HPLC)
Melting point	111-114 °C

03 /Safety & handling

GHS hazard pictogram: Toxic (GHS06) — Toxic

Danger

Hazard statements

H301Toxic if swallowed

Precautionary statements

P301IF SWALLOWED

Protective equipment	dust mask type N95 (US), Eyeshields, Faceshields, Gloves
Transport (UN / ADR)	UN 2811 6.1 / PGIII
Water hazard class (WGK, DE)	3
Hazard codes (EU)	Xn
Risk statements (R)	22

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

156942-67-5

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is (R)-α-Methoxy-2-naphthylacetic acid used for?

This compound is primarily used as a chiral building block in asymmetric synthesis and organic chemistry research for the preparation of enantiomerically pure target molecules.

What are the CAS number and molecular formula?

The CAS number is 156942-67-5, and the molecular formula is C13H12O3.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies (R)-α-Methoxy-2-naphthylacetic acid with an assay of ≥99.0% (HPLC) and enantiomeric excess of ≥99.0% (HPLC). This product is a research grade material and not intended for pharmaceutical, food, or any other regulated applications unless explicitly stated.

How should (R)-α-Methoxy-2-naphthylacetic acid be handled?

This compound is classified as toxic if swallowed (H301) and requires careful handling. Personnel should wear appropriate personal protective equipment, including a dust mask (N95), eyeshields, faceshields, and gloves. Ensure adequate ventilation and avoid dust formation.

Is this product suitable for export?

Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including (R)-α-Methoxy-2-naphthylacetic acid, adhering to all international shipping regulations.