(R)-α-Methyl-2-pyridinemethanol
(R)-α-Methyl-2-pyridinemethanol (CAS 27911-63-3), with the molecular formula C7H9NO and a molecular weight of 123.15 g/mol, is a valuable chiral building block. This heterocyclic compound is recognised for its specific optical activity, making it a key intermediate in asymmetric synthesis. It serves as a crucial component in the preparation of complex molecules where stereochemistry is paramount, finding utility in various chemical synthesis pathways.
- IUPAC
- (R)-1-(2-Pyridyl)-ethanol,(R)-2-(1-Hydroxyethyl)pyridine
Asymmetric Synthesis
Utilised as a chiral building block in enantioselective synthesis, enabling the creation of stereochemically pure target molecules. Its defined optical rotation is critical for controlling the stereochemistry of subsequent reactions.
Pharmaceutical Intermediate
Serves as a key intermediate in the synthesis of active pharmaceutical ingredients (APIs) where precise stereochemical control is essential for efficacy and safety. Its pyridine core and chiral centre are valuable structural motifs.
Chemical Synthesis
Applied broadly in organic synthesis as a functionalised pyridine derivative for constructing more complex heterocyclic systems. Its reactivity allows for diverse derivatisation.
Chiral Ligand Precursor
Can be employed in the development of chiral ligands for metal-catalyzed asymmetric reactions, contributing to the field of catalysis.
| Molecular weight | 123.15 |
|---|---|
| Empirical formula | C7H9NO |
| Assay | ≥98.0% (GC) |
| Refractive index | n20/D 1.528 |
| Optical activity | [α]/D +62.0±2.0°, c = 1 in ethanol |
| Optical purity | enantiomeric ratio: ≥99.0:1.0 (GC) |
| Storage temperature | 2-8°C |
Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H318Causes serious eye damage
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-37/38-41 |
| Safety statements (S) | 26-39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (R)-α-Methyl-2-pyridinemethanol primarily used for?
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It is primarily used in asymmetric synthesis and as a chiral building block in chemical synthesis, particularly for pharmaceutical intermediates where precise stereochemistry is required.
What are the CAS number and formula for (R)-α-Methyl-2-pyridinemethanol?
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The CAS number is 27911-63-3 and the empirical formula is C7H9NO.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (R)-α-Methyl-2-pyridinemethanol with an assay of ≥98.0% (GC) and an optical purity of enantiomeric ratio: ≥99.0:1.0 (GC). We do not represent this product as USP, BP, EP, or other pharmacopoeia grades.
How should (R)-α-Methyl-2-pyridinemethanol be handled safely?
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Handling requires caution due to its hazards (H302-H315-H318-H335). Use appropriate personal protective equipment including a dust mask (N95), eyeshields, face shield, and gloves. Ensure adequate ventilation and avoid contact with eyes, skin, and clothing.
How is this chemical typically packaged and shipped?
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This chemical is typically stored at 2-8°C. Packaging and export adhere to international shipping regulations for chemical substances.
How can I request a quote or sample for (R)-α-Methyl-2-pyridinemethanol?
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Please contact our sales team via the website or direct email to request a quotation or to arrange for a sample.
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