(R)-α-Methyl-4-nitrobenzylamine hydrochloride
(R)-α-Methyl-4-nitrobenzylamine hydrochloride (CAS 57233-86-0) is a chiral amine salt with the chemical formula O2NC6H4CH(CH3)NH2 · HCl and a molecular weight of 202.64 g/mol. This compound serves as a valuable building block in organic synthesis, particularly in asymmetric synthesis and chiral resolution processes. Its specific stereochemistry makes it a key intermediate for creating enantiomerically pure compounds.
- IUPAC
- (R)-1-(4-Nitrophenyl)ethylamine hydrochloride

Chiral Building Block
Utilised in the synthesis of complex chiral molecules, pharmaceutical intermediates, and fine chemicals where specific stereochemistry is critical for biological activity or material properties.
Asymmetric Synthesis
A key reagent in asymmetric synthesis to introduce or control chirality in target molecules, enabling the production of enantiomerically enriched products.
Chiral Resolution
Employed as a resolving agent for the separation of racemic mixtures into individual enantiomers, facilitating the purification of chiral compounds.
Organic Synthesis Intermediate
Serves as a versatile intermediate in multi-step organic syntheses, contributing the 4-nitrophenyl-ethylamine moiety to larger molecular structures.
| Molecular weight | 202.64 |
|---|---|
| Linear formula | O2NC6H4CH(CH3)NH2 · HCl |
| Assay | ≥99.0% (HPLC) |
| Grade | puriss. |
| Optical activity | [α]20/D +7.2±0.5°, c = 1% in 0.05 M NaOH |
| Melting point | 248-250 °C(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (R)-α-Methyl-4-nitrobenzylamine hydrochloride used for?
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It is primarily used as a chiral building block and resolving agent in asymmetric synthesis and organic chemical synthesis for creating enantiomerically pure compounds.
What is the CAS number and chemical formula for (R)-α-Methyl-4-nitrobenzylamine hydrochloride?
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The CAS number is 57233-86-0 and the chemical formula is O2NC6H4CH(CH3)NH2 · HCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this compound at a puriss. grade with an assay of ≥99.0% (HPLC). We do not represent it as USP, BP, or EP grade.
What are the safety considerations for handling (R)-α-Methyl-4-nitrobenzylamine hydrochloride?
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This compound is classified as a Warning. It causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Use a dust mask type N95, eyeshields, and gloves. Ensure good ventilation and avoid breathing dust.
Is (R)-α-Methyl-4-nitrobenzylamine hydrochloride a controlled substance?
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The provided data does not indicate that this compound is a controlled substance.
How is (R)-α-Methyl-4-nitrobenzylamine hydrochloride packed and exported?
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Tech Serve Solutions, as a global supplier and exporter, ensures appropriate packaging and adherence to all regulations for shipping this chemical internationally.
How can I request a sample or quote for (R)-α-Methyl-4-nitrobenzylamine hydrochloride?
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Please contact our sales team through the website or by phone to request a sample or a quotation for this product.
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