2-(Trifluoromethyl)benzoyl chloride
2-(Trifluoromethyl)benzoyl chloride (CAS: 312-94-7) is a key organic building block with the linear formula CF₃C₆H₄COCl and a molecular weight of 208.56 g/mol. This acid halide serves as a versatile reagent in chemical synthesis, particularly for introducing the 2-(trifluoromethyl)benzoyl group into various molecules. It is essential for the preparation of complex organic compounds and pharmaceutical intermediates, valued for its reactivity and specific structural contribution.
- IUPAC
- α,α,α-Trifluoro-o-toluoyl chloride
- Synonyms
- α,α,α-Trifluoro-o-toluoyl chloride
Chemical Synthesis Intermediate
2-(Trifluoromethyl)benzoyl chloride is utilised as a crucial intermediate in the synthesis of diverse organic molecules. Its acyl chloride functionality readily reacts with nucleophiles, making it a valuable component in multi-step synthetic pathways.
Pharmaceutical and Agrochemical Development
This compound serves as a building block for the development of novel pharmaceuticals and agrochemicals. The trifluoromethyl group often imparts desirable properties such as increased lipophilicity and metabolic stability to target molecules.
Research and Development
Researchers employ 2-(Trifluoromethyl)benzoyl chloride in laboratory settings for exploring new chemical reactions and developing innovative materials. Its well-defined structure and reactivity support a wide range of academic and industrial R&D projects.
| Molecular weight | 208.56 |
|---|---|
| Linear formula | CF3C6H4COCl |
| Assay | 99% |
| Boiling point | 84-85 °C/16 mmHg(lit.) |
| Density | 1.416 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.479(lit.) |
| Application | 2-(Trifluoromethyl)benzoyl chloride may be used in chemical synthesis. |
Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 96 °C / 204.8 °F |
| Transport (UN / ADR) | UN 3265 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34-37 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-(Trifluoromethyl)benzoyl chloride primarily used for?
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2-(Trifluoromethyl)benzoyl chloride is primarily used as an intermediate and building block in chemical synthesis, particularly for introducing the 2-(trifluoromethyl)benzoyl moiety into organic molecules.
What is the CAS number and chemical formula for 2-(Trifluoromethyl)benzoyl chloride?
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The CAS number for 2-(Trifluoromethyl)benzoyl chloride is 312-94-7, and its linear chemical formula is CF₃C₆H₄COCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-(Trifluoromethyl)benzoyl chloride with an assay of 99%. We do not represent this product as USP, BP, EP, or other pharmacopoeia grades.
How should 2-(Trifluoromethyl)benzoyl chloride be handled safely?
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Due to its corrosive nature (H314), handle 2-(Trifluoromethyl)benzoyl chloride with extreme care. Wear appropriate personal protective equipment, including a faceshield, full-face respirator, chemical-resistant gloves, and eye protection. Ensure adequate ventilation and follow stringent safety protocols.
Is 2-(Trifluoromethyl)benzoyl chloride suitable for export?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including 2-(Trifluoromethyl)benzoyl chloride, adhering to international shipping regulations.
How can I request a sample or quote for 2-(Trifluoromethyl)benzoyl chloride?
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To request a sample or a quotation for 2-(Trifluoromethyl)benzoyl chloride, please contact our sales department through the designated channels on the Tech Serve Solutions website.
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