(2-Hydroxyethyl)triphenylphosphonium chloride
(2-Hydroxyethyl)triphenylphosphonium chloride (CAS 23250-03-5) is a chemical reagent with the linear formula HOCH2CH2P(C6H5)3Cl and a molecular weight of 342.80 g/mol. This compound serves as a valuable tool in organic synthesis, primarily utilised in Wittig reactions for the formation of carbon-carbon double bonds. Its applications span various chemical synthesis pathways, positioning it as a key synthetic reagent for olefination processes.

Wittig Reaction Reagent
This phosphonium salt is a precursor for ylide formation in the Wittig reaction. It enables the stereoselective synthesis of alkenes from carbonyl compounds, playing a critical role in C-C bond formation.
Olefination Reactions
As a Wittig reagent derivative, it facilitates the conversion of aldehydes and ketones into alkenes. This is a fundamental transformation in organic chemistry for constructing complex molecular frameworks.
Chemical Synthesis
Its utility extends to general chemical synthesis, providing a reliable method for introducing specific functional groups and building molecular complexity through controlled reactions.
| Molecular weight | 342.80 |
|---|---|
| Linear formula | HOCH2CH2P(C6H5)3Cl |
| Assay | ≥98.0% |
| Application | Reagent for:• Wittig reaction1 |
| Melting point | 234-235 °C (dec.)(lit.)238-240 °C (dec.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (2-Hydroxyethyl)triphenylphosphonium chloride used for?
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(2-Hydroxyethyl)triphenylphosphonium chloride is primarily used as a reagent in Wittig reactions for the synthesis of alkenes and in general C-C bond formation and olefination processes.
What is the CAS number and formula for (2-Hydroxyethyl)triphenylphosphonium chloride?
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The CAS number is 23250-03-5 and the linear formula is HOCH2CH2P(C6H5)3Cl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (2-Hydroxyethyl)triphenylphosphonium chloride with an assay of ≥98.0%. We do not represent this product as USP, BP, or EP grade.
How should (2-Hydroxyethyl)triphenylphosphonium chloride be handled safely?
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This compound is classified as a warning substance and may cause skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). Handle with appropriate personal protective equipment, including eyeshields, gloves, and a dust mask (type N95 or equivalent), and ensure adequate ventilation.
Is (2-Hydroxyethyl)triphenylphosphonium chloride a controlled substance?
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There is no indication in the provided data that (2-Hydroxyethyl)triphenylphosphonium chloride is a controlled substance.
How is (2-Hydroxyethyl)triphenylphosphonium chloride packed and shipped?
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Products are carefully packed according to international shipping regulations. Tech Serve Solutions is a specialist global supplier and exporter experienced in handling and exporting fine chemicals.
How can I request a sample or quote for (2-Hydroxyethyl)triphenylphosphonium chloride?
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To request a sample or a quotation, please contact our sales team through the website or by direct inquiry, providing your specific requirements.
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