(2-Hydroxypropyl)-α-cyclodextrin
(2-Hydroxypropyl)-α-cyclodextrin (CAS 128446-33-3) is a chemically modified cyclodextrin with an average molecular weight of approximately 1,180. It exhibits an optical activity of +125° at 20/D and a molar substitution of 0.6. This compound serves as a versatile reagent in analytical chemistry, particularly in chromatography and capillary electrophoresis, and finds use in chemical synthesis and chelation applications.
Analytical Chromatography
Utilised as a chiral mobile phase additive in High-Performance Liquid Chromatography (HPLC) and gas chromatography for the separation of enantiomers.
Capillary Electrophoresis
Acts as a chiral selector in capillary electrophoresis (CE) to resolve enantiomeric compounds.
Chemical Synthesis
Employed as a reagent or building block in synthetic organic chemistry for complex molecule construction.
Chelation and Complexation
Functions as a complexing agent, forming inclusion complexes with various guest molecules.
| Optical activity | [α]20/D +125°, c = 1 in H2O |
|---|---|
| Melting point | 245 °C (dec.)(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Mol Wt | average Mw ~1,180 |
|---|---|
| Extent Of Labeling | 0.6 molar substitution |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (2-Hydroxypropyl)-α-cyclodextrin used for?
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(2-Hydroxypropyl)-α-cyclodextrin is used in analytical chemistry, including chromatography and capillary electrophoresis, as well as in chemical synthesis and for chelation/complexation applications.
What is the CAS number and formula for (2-Hydroxypropyl)-α-cyclodextrin?
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The CAS number is 128446-33-3. The chemical formula is not provided in the data.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (2-Hydroxypropyl)-α-cyclodextrin with an extent of labelling of 0.6 molar substitution and an average molecular weight of ~1,180. It is supplied as a technical/research grade, and TSS does not represent it as USP, BP, EP, or any other pharmacopoeia grade.
What are the safety and handling recommendations for this compound?
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Handling requires appropriate personal protective equipment, including eyeshields, gloves, and a type N95 (US) or type P1 (EN143) respirator filter. The compound has a GHS classification of 3 for WGK Germany. It has a melting point of 245 °C with decomposition.
How is (2-Hydroxypropyl)-α-cyclodextrin packed, shipped, and exported?
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Tech Serve Solutions specialises in the global supply and export of fine chemicals and reagents, ensuring appropriate packaging and adherence to international shipping regulations.
How can I request a sample or a quote for this product?
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To request a sample or a quote for (2-Hydroxypropyl)-α-cyclodextrin, please contact our sales department through the TSS website or by calling our direct line.
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