(2-Hydroxybenzyl)triphenylphosphonium bromide
(2-Hydroxybenzyl)triphenylphosphonium bromide (CAS: 70340-04-4; Formula: HOC6H4CH2P(C6H5)3Br) is a phosphonium salt with a molecular weight of 451.34 g/mol. This reagent serves as a valuable intermediate in organic synthesis. Its primary application lies in Wittig-type reactions for the formation of carbon-carbon double bonds, facilitating the synthesis of various organic molecules. It is a key component in chemical synthesis, particularly for olefination processes.
Wittig Reagent for Olefination
(2-Hydroxybenzyl)triphenylphosphonium bromide acts as a Wittig reagent precursor. Upon deprotonation, it generates a ylide that reacts with aldehydes or ketones to form alkenes, a fundamental transformation in organic chemistry.
C-C Bond Formation
This compound is instrumental in creating new carbon-carbon bonds, a cornerstone of complex molecule synthesis. It enables the introduction of a specific structural motif derived from the 2-hydroxybenzyl group.
Organic Synthesis Intermediate
As a versatile synthetic reagent, it finds use in multi-step syntheses for pharmaceuticals, agrochemicals, and materials science research, allowing for controlled alkene formation.
| Molecular weight | 451.34 |
|---|---|
| Linear formula | HOC6H4CH2P(C6H5)3Br |
| Assay | 98% |
| Melting point | 242-245 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (2-Hydroxybenzyl)triphenylphosphonium bromide used for?
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(2-Hydroxybenzyl)triphenylphosphonium bromide is primarily used as a Wittig reagent precursor for olefination reactions and C-C bond formation in organic synthesis.
What is the CAS number and formula for (2-Hydroxybenzyl)triphenylphosphonium bromide?
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The CAS number is 70340-04-4 and the linear formula is HOC6H4CH2P(C6H5)3Br.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (2-Hydroxybenzyl)triphenylphosphonium bromide with an assay of 98%. TSS does not represent this product as USP, BP, or EP grade.
How should (2-Hydroxybenzyl)triphenylphosphonium bromide be handled?
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Handle with appropriate personal protective equipment, including a dust mask (type N95 US), eyeshields, and gloves. Avoid breathing dust and ensure adequate ventilation. This compound is classified as an irritant to skin, eyes, and respiratory tract (H315, H319, H335).
Is this chemical shipped internationally?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including (2-Hydroxybenzyl)triphenylphosphonium bromide.
How can I request a quote or sample?
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Please contact our sales department via the website or direct phone line to request a quote or sample of (2-Hydroxybenzyl)triphenylphosphonium bromide.
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